Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859865 | 0.97 | DPP8 (0.38) | DPP8DPP9PSEN1PSEN2APH1B | |
| SCHEMBL7860568 | 0.93 | HTT (0.38) | DPP8DPP9PSEN1PSEN2APH1B | |
| SCHEMBL7859712 | 0.92 | DPP8 (0.39) | DPP8DPP9PSEN1PSEN2APH1B | |
| SCHEMBL7860576 | 0.92 | DPP8 (0.39) | DPP8DPP9PSEN1PSEN2APH1B | |
| SCHEMBL7858333 | 0.90 | MAOB (0.39) | DPP8DPP9PSEN1PSEN2APH1B | |
| SCHEMBL7854735 | 0.90 | DPP8 (0.36) | DPP8DPP9PSEN1PSEN2APH1B | |
| SCHEMBL7860059 | 0.88 | ATM (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7861793 | 0.87 | ECE1 (0.36) | DPP8DPP9ALDH1A1ATMHTT | |
| SCHEMBL7852750 | 0.86 | DPP8 (0.43) | DPP8DPP9PSEN1PSEN2APH1B | |
| SCHEMBL8583297 | 0.85 | DPP8 (0.40) | DPP8DPP9PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747381-B1 | CARBAPENEM DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| EP-0747381-A1 | CARBAPENEM DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |