Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9039568 | 0.89 | ATM (0.41) | ATMTDP1HTTCCR5ALDH1A1 | |
| SCHEMBL10862981 | 0.89 | ATM (0.41) | ATMTDP1HTTCCR5ALDH1A1 | |
| SCHEMBL7859871 | 0.88 | DPP8 (0.40) | ATMTDP1PSEN1PSEN2APH1B | |
| SCHEMBL9368309 | 0.88 | ALDH1A1 (0.41) | ATMTDP1RAB9AHTTALDH1A1 | |
| SCHEMBL10861401 | 0.88 | ALDH1A1 (0.41) | ATMTDP1RAB9AHTTALDH1A1 | |
| SCHEMBL7859860 | 0.88 | ATM (0.42) | ATMTDP1RAB9ACCR5 | |
| SCHEMBL9041342 | 0.87 | ATM (0.40) | ATMTDP1HTTCCR5ALDH1A1 | |
| SCHEMBL10371377 | 0.87 | ALDH1A1 (0.39) | ATMTDP1RAB9AHTTALDH1A1 | |
| SCHEMBL10390470 | 0.87 | ATM (0.39) | ATMTDP1RAB9AHTTALDH1A1 | |
| SCHEMBL7860568 | 0.86 | HTT (0.38) | ATMTDP1PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747381-B1 | CARBAPENEM DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5707987-A | BACTERICIDE ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0747381-A1 | CARBAPENEM DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |