Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 12/20 | 0.61 |
| ▸ | ESR1 | P03372 | 8/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | PLD2 | O14939 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | C5 | P01031 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8898650 | 0.86 | ESR1 (0.72) | ESR1ESR2MEN1ALDH1A1LMNA | |
| SCHEMBL7852990 | 0.85 | ESR1 (0.67) | ESR1ESR2MEN1ALDH1A1LMNA | |
| SCHEMBL3667715 | 0.83 | ESR1 (0.68) | ESR1ESR2MEN1ALDH1A1LMNA | |
| SCHEMBL8901779 | 0.82 | ESR1 (0.47) | ESR1ESR2MEN1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL4608177 | 0.82 | ESR1 (0.68) | ESR1ESR2MEN1ALDH1A1LMNA | |
| SCHEMBL6836522 | 0.81 | F2 (0.89) | F2ESR1ESR2MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5858600 | 0.80 | F2 (0.88) | F2ESR1ESR2MEN1ALDH1A1 | |
| SCHEMBL7622096 | 0.80 | F2 (0.81) | F2ESR1ESR2MEN1ALDH1A1 | |
| SCHEMBL7621321 | 0.80 | F2 (0.91) | F2ESR1ESR2MEN1ALDH1A1 | |
| SCHEMBL7860060 | 0.80 | ESR1 (0.69) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791591-B1 | Benzothiophenes, formulations containing same, and methods for their préparation | LILLY CO ELI (US) | 2001-08-29 | — | — | EP | disclosed |
| EP-0791591-A1 | Benzothiophenes, formulations containing same, and methods | ELI LILLY AND COMPANY (US) | 1997-08-27 | — | — | EP | disclosed |