Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KHK | P50053 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 6/20 | 0.46 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11343167 | 0.95 | KHK (0.52) | POLBKHKKMT2AALDH1A1MAPT | |
| SCHEMBL678709 | 0.86 | POLB (0.44) | POLBKHKKMT2AMAPTLTA4H | |
| SCHEMBL465990 | 0.86 | POLB (0.44) | POLBKHKKMT2AMAPTLTA4H | |
| SCHEMBL466055 | 0.86 | POLB (0.51) | POLBKHKKMT2ALTA4H | |
| SCHEMBL465870 | 0.86 | KHK (0.51) | POLBKHKALDH1A1MAPTL3MBTL1 | |
| SCHEMBL1779920 | 0.84 | POLB (0.46) | POLBKMT2AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL1779921 | 0.84 | POLB (0.46) | POLBKMT2AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL679264 | 0.84 | LTA4H (0.54) | POLBKHKLTA4H | |
| SCHEMBL11805775 | 0.84 | KHK (0.52) | POLBKHKALDH1A1MAPTL3MBTL1 | |
| SCHEMBL8594147 | 0.82 | KHK (0.46) | POLBKHKKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103254154-A | Novel method for preparing mesylate pridinol | CHONGQING BEIBEI RES INST OF MODERN APPLIED MEDICINES | 2013-08-21 | — | — | CN | disclosed |
| EP-0736509-B1 | Processes for preparing optically active alcohols and optically active amines | SUMITOMO CHEMICAL CO (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-6025531-A | REACTING A PROCHIRAL KETONE WITH A MIXTURE BORON-CONTAINING COMPOUNDS HAVING A BORANE REACTION PRODUCT FROM OPTICALLY ACTIVE BETA-AMINOALCOHOL AND A BORON HYDRIDE OR A METAL BOROHYDRIDE, AND AN OPTICALLY ACTIVE OXAZABOROLIDINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-15 | — | — | US | disclosed |
| US-5801280-A | Processes for preparing optically active alcohols and optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-09-01 | — | — | US | disclosed |
| EP-0736509-A2 | Processes for preparing optically active alcohols and optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-10-09 | — | — | EP | disclosed |