Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 9/20 | 0.66 |
| ▸ | DRD2 | P14416 | 5/20 | 0.66 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854627 | 0.88 | DRD3 (0.67) | DRD3DRD2FYN | |
| SCHEMBL7861355 | 0.86 | DRD3 (0.55) | DRD3DRD2HTR1AFYN | |
| SCHEMBL7860284 | 0.85 | DRD3 (0.63) | DRD3DRD2FYN | |
| SCHEMBL8900096 | 0.83 | DRD3 (0.61) | DRD3DRD2FYN | |
| SCHEMBL7864930 | 0.83 | DRD3 (0.61) | DRD3DRD2FYN | |
| SCHEMBL7864498 | 0.82 | DRD3 (0.51) | DRD3DRD2HTR1A | |
| SCHEMBL626977 | 0.78 | DRD3 (1.00) | DRD3DRD2DRD4 | |
| SCHEMBL29448456 | 0.78 | DRD3 (1.00) | DRD3DRD2DRD4 | |
| SCHEMBL8899133 | 0.77 | DRD3 (0.60) | DRD3DRD2HTR1AFYNDRD4 | |
| SCHEMBL7862705 | 0.77 | DRD3 (0.60) | DRD3DRD2HTR1AFYNDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807101-B1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | UPJOHN CO (US) | 2001-06-13 | — | — | EP | disclosed |
| US-5936000-A | 2-aminoindans as selective dopamine D3 ligands | PHARMACIA & UPJOHN COMPANY (US) | 1999-08-10 | — | — | US | disclosed |
| WO-1996023760-A1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 1996-08-08 | — | — | WO | disclosed |