Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 14/20 | 0.61 |
| ▸ | DRD2 | P14416 | 10/20 | 0.61 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864930 | 1.00 | DRD3 (0.61) | DRD3DRD2MLNRFYN | |
| SCHEMBL7854627 | 0.84 | DRD3 (0.67) | DRD3DRD2MLNRFYN | |
| SCHEMBL7860144 | 0.83 | DRD3 (0.66) | DRD3DRD2FYN | |
| SCHEMBL7860284 | 0.83 | DRD3 (0.63) | DRD3DRD2MLNRFYN | |
| SCHEMBL7862420 | 0.82 | DRD3 (0.54) | DRD3DRD2FYN | |
| SCHEMBL8692148 | 0.82 | DRD3 (0.54) | DRD3DRD2FYN | |
| SCHEMBL7854607 | 0.75 | DRD3 (0.51) | DRD3DRD2FYN | |
| SCHEMBL626977 | 0.74 | DRD3 (1.00) | DRD3DRD2 | |
| SCHEMBL29448456 | 0.74 | DRD3 (1.00) | DRD3DRD2 | |
| SCHEMBL9776918 | 0.73 | DRD3 (0.61) | DRD3DRD2FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807101-A1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-19 | — | — | EP | disclosed |