Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.59 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | PPARG | P37231 | 4/20 | 0.50 |
| ▸ | PPARD | Q03181 | 4/20 | 0.50 |
| ▸ | PPARA | Q07869 | 4/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.50 |
| ▸ | TLR2 | O60603 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL9811797 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22FFAR4 | |
| SCHEMBL16140282 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22FFAR4 | |
| SCHEMBL17477592 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22FFAR4 | |
| SCHEMBL11809460 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22FFAR4 | |
| SCHEMBL5926323 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22FFAR4 | |
| Adipic Acid SCHEMBL6361755 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22FFAR4 | |
| SCHEMBL39651 | 0.97 | LMNA (0.61) | TSHRLMNANFKB1PMP22FFAR4 | |
| SCHEMBL1258357 | 0.89 | — | — | |
| Arachidic Acid SCHEMBL17812737 | 0.89 | FFAR4 (0.78) | TSHRFFAR4FFAR1GPR84ALDH1A1 | |
| Palmitic Acid SCHEMBL17812630 | 0.89 | FFAR4 (0.78) | TSHRFFAR4FFAR1GPR84ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124820-A1 | LIPOIC ACID DERIVATIVES AND THEIR USE IN TREATMENT OF DISEASE | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000024734-A1 | LIPOIC ACID DERIVATIVES AND THEIR USE IN TREATMENT OF DISEASE | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2000-05-04 | — | — | WO | disclosed |
| EP-0835251-A1 | PROCESS FOR THE PRODUCTION OF LIPOIC ACID | ASTA Medica Aktiengesellschaft (DE) | 1998-04-15 | — | — | EP | disclosed |