Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL856295 | 0.94 | PIK3CA (0.47) | PIK3CAALDH1A1CYP2C19LMNAHIF1A | |
| SCHEMBL7823835 | 0.91 | PIK3CA (0.48) | PIK3CAALDH1A1CYP2C19LMNAHIF1A | |
| SCHEMBL856212 | 0.90 | PIK3CA (0.49) | PIK3CAALDH1A1CYP2C19LMNAHIF1A | |
| SCHEMBL855583 | 0.88 | PIK3CA (0.49) | PIK3CAALDH1A1CYP2C19LMNAHIF1A | |
| SCHEMBL856472 | 0.88 | PIK3CA (0.47) | PIK3CAALDH1A1CYP2C19LMNAHIF1A | |
| SCHEMBL858779 | 0.87 | PIK3CA (0.48) | PIK3CAALDH1A1CYP2C19LMNAHIF1A | |
| SCHEMBL856159 | 0.87 | PIK3CA (0.45) | PIK3CAALDH1A1CYP2C19LMNAHIF1A | |
| SCHEMBL856354 | 0.87 | PIK3CA (0.47) | PIK3CAALDH1A1CYP2C19LMNAHIF1A | |
| SCHEMBL7816643 | 0.86 | PIK3CA (0.47) | PIK3CAALDH1A1CYP2C19LMNAHIF1A | |
| SCHEMBL857459 | 0.85 | PIK3CA (0.45) | PIK3CAALDH1A1CYP2C19LMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010135524-A1 | BENZOXAZEPINES BASED P13K/MT0R INHIBITORS AGAINST PROLIFERATIVE DISEASES | EXELIXIS, INC. (US) | 2010-11-25 | — | — | WO | disclosed |