SCHEMBL7860355

SCHEMBL7860355

CC(C)(C)OC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACE P12821 1/20 0.66
CTSS P25774 4/20 0.62
CTSK P43235 3/20 0.62
CTSB P07858 2/20 0.62
CTSL P07711 1/20 0.62
REN P00797 4/20 0.55
PPARA Q07869 2/20 0.55
PPARG P37231 1/20 0.55
AKT1 P31749 1/20 0.54
ITGB3 P05106 1/20 0.54
ITGA2B P08514 1/20 0.54
APP P05067 1/20 0.53
ATM Q13315 1/20 0.53
KMT2A Q03164 1/20 0.53
KLK5 Q9Y337 1/20 0.53
MAPK1 P28482 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29964830 0.95 CTSS (0.65) ACECTSSCTSKCTSBCTSL
SCHEMBL10050068 0.92 ACE (0.72) ACECTSSCTSKCTSBCTSL
SCHEMBL29484189 0.92 ACE (0.72) ACECTSSCTSKCTSBCTSL
SCHEMBL21219305 0.92 ACE (0.72) ACECTSSCTSKCTSBCTSL
SCHEMBL9551322 0.92 ACE (0.72) ACECTSSCTSKCTSBCTSL
SCHEMBL15671562 0.92 ACE (0.72) ACECTSSCTSKCTSBCTSL
SCHEMBL2367371 0.92 ACE (0.72) ACECTSSCTSKCTSBCTSL
SCHEMBL30688549 0.92 ACE (0.72) ACECTSSCTSKCTSBCTSL
SCHEMBL29105495 0.92 ACE (0.65) ACECTSSCTSKCTSBCTSL
SCHEMBL29105496 0.92 ACE (0.65) ACECTSSCTSKCTSBCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024476-A diphenylphosphonooxy-X-phenol compound, preparation method and application in preparation of aspartame 西北工业大学 2023-11-10 CN disclosed
US-6180759-B1 PREPARING AZACYCLOALKANOYLPSEUDOTETRAPEPTIDES COMPRISING COUPLING A DIPEPTIDE WITH A PSEUDODIPEPTIDE; FOR EXAMPLE, N-(N-ETHYL-N-(1-OXO-4-(4-PIPERIDINYL)BUTYL)GLYCYL)-(L)-ALPHA-ASPARTYL-3 -CYCLOHEXYL-(L)-ALANINEAMIDE; USE AS ANTICOAGULANTS AVENTIS PHARMACEUTICALS PRODUCTS INC. 2001-01-30 US disclosed