Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.43 |
| ▸ | CA1 | P00915 | 10/20 | 0.43 |
| ▸ | CA12 | O43570 | 7/20 | 0.43 |
| ▸ | CA9 | Q16790 | 6/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7858337 | 0.87 | CA2 (0.40) | CA2CA1CA12CA9CA7 | |
| SCHEMBL9519145 | 0.86 | MAPT (0.39) | MAPTRAB9AALDH1A1TDP1 | |
| SCHEMBL10699078 | 0.81 | TDP1 (0.39) | MAPTRAB9AALDH1A1TDP1 | |
| SCHEMBL9520226 | 0.81 | TDP1 (0.39) | MAPTRAB9AALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL9520292 | 0.80 | TDP1 (0.38) | MAPTRAB9AALDH1A1TDP1 | |
| SCHEMBL9519619 | 0.79 | TDP1 (0.39) | MAPTRAB9AALDH1A1TDP1 | |
| SCHEMBL7852631 | 0.79 | TDP1 (0.45) | MAPTRAB9AALDH1A1TDP1CCR5 | |
| SCHEMBL9518928 | 0.78 | TDP1 (0.35) | MAPTRAB9AALDH1A1TDP1 | |
| SCHEMBL10390151 | 0.78 | TDP1 (0.44) | MAPTRAB9AALDH1A1TDP1 | |
| SCHEMBL10861535 | 0.78 | TDP1 (0.44) | MAPTRAB9AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747381-B1 | CARBAPENEM DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5707987-A | BACTERICIDE ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0747381-A1 | CARBAPENEM DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |