Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11468007 | 0.79 | APP (0.64) | APPHDAC1HDAC8HDAC6KMT2A | |
| SCHEMBL4310746 | 0.79 | APP (0.50) | APPKIF11HDAC1HDAC8HDAC6 | |
| SCHEMBL13527786 | 0.78 | HSD17B10 (0.61) | TDP1HSD17B10KMT2AMEN1CYP2C9 | |
| Hexaprofen SCHEMBL2111016 | 0.77 | APP (0.67) | APPHAO1KMT2ACYP2C9HTT | |
| SCHEMBL27752440 | 0.77 | APP (0.52) | APPKIF11HDAC1HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL9222908 | 0.76 | APP (0.48) | APPKIF11HDAC1HDAC8HDAC6 | |
| SCHEMBL11833494 | 0.75 | APP (0.50) | APPKIF11HDAC1HDAC8HDAC6 | |
| SCHEMBL3162884 | 0.75 | SLC7A5 (0.57) | KIF11TDP1HSD17B10KMT2AMEN1 | |
| SCHEMBL5803409 | 0.75 | APP (0.53) | APPKIF11HDAC1HDAC8HDAC6 | |
| SCHEMBL11841041 | 0.75 | APP (0.50) | APPKIF11HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010130007-A1 | ANTIMICROBIAL COMPOUNDS | MONASH UNIVERSITY (AU) | 2010-11-18 | — | — | WO | disclosed |