Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 11/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.50 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.50 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11468007 | 0.98 | APP (0.64) | APPPTGS1PTGS2MT-CO1MT-CO2 | |
| SCHEMBL2436189 | 0.91 | APP (0.56) | APPPTGS1PTGS2MT-CO1MT-CO2 | |
| SCHEMBL10443245 | 0.87 | APP (0.53) | APPHTTKMT2ANAAAHAO1 | |
| SCHEMBL11428636 | 0.84 | APP (0.51) | APPPTGS1PTGS2MT-CO1MT-CO2 | |
| SCHEMBL5803409 | 0.83 | APP (0.53) | APPHTTKMT2ANAAAHAO1 | |
| SCHEMBL9643202 | 0.82 | PTGS1 (0.51) | APPPTGS1PTGS2MT-CO1MT-CO2 | |
| SCHEMBL13494635 | 0.81 | APP (0.48) | APPPTGS1PTGS2MT-CO1MT-CO2 | |
| SCHEMBL4310746 | 0.81 | APP (0.50) | APPHTTKMT2ANAAAHAO1 | |
| SCHEMBL9692258 | 0.80 | NAAA (0.48) | APPNAAAHAO1 | |
| SCHEMBL27752440 | 0.79 | APP (0.52) | APPHTTKMT2ANAAAHAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118801434-A | Multi-source access energy management method and system for charging, replacing and storing integrated station | 国网商用电动汽车投资有限责任公司 | 2024-10-18 | — | — | CN | claimed |
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| CN-101330905-A | Freeze-drying process and products obtained thereby | SCIDOSE LLC (US) | 2008-12-24 | — | — | CN | claimed |
| EP-1968935-A1 | SUBSTITUTED BIS(HETERO)AROMATIC N-ETHYLPROPIOLAMIDES AND USE THEREOF FOR PRODUCTION OF MEDICAMENTS | Grünenthal GmbH (DE) | 2008-09-17 | — | — | EP | claimed |
| EP-1954244-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | Scidose, Llc (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007079958-A1 | SUBSTITUTED BIS(HETERO)AROMATIC N-ETHYLPROPIOLAMIDES AND USE THEREOF FOR PRODUCTION OF MEDICAMENTS | Grünenthal GmbH (DE) | 2007-07-19 | — | — | WO | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| US-20060252938-A1 | Process for the separation of palladium catalyst from crude reaction mixtures of aryl acetic acids obtained by carbonylation | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-09 | — | — | US | claimed |
| US-5380867-A | Selective precipitation of α-aryl carboxylic acid salts | HOECHST CELANESE CORPORATION (US) | 1995-01-10 | — | — | US | claimed |
| WO-1994012451-A1 | SELECTIVE PRECIPITATION OF α-ARYL CARBOXYLIC ACID SALTS | HOECHST CELANESE CORPORATION (US) | 1994-06-09 | — | — | WO | claimed |
| EP-0274146-B1 | PROCESS FOR THE PREPARATION OF 2-ARYLPROPIONIC ACIDS | GIST-BROCADES N.V. (NL) | 1992-04-01 | — | — | EP | claimed |
| EP-0205215-B1 | PROCESS FOR THE PREPARATION OF 2-ARYLPROPIONIC ACIDS | GIST-BROCADES N.V. (NL) | 1990-08-08 | — | — | EP | claimed |
| US-4886750-A | STEREOSELECTIVE HYDROLYSIS USING MICROORGANISMS | GIST-BROCADES N.V. (NL) | 1989-12-12 | — | — | US | claimed |
| EP-0274146-A1 | Process for the preparation of 2-arylpropionic acids | GIST-BROCADES N.V. (NL) | 1988-07-13 | — | — | EP | claimed |
| CN-87100031-A | The preparation method of 2-arylpropionic acid | — | 1987-09-09 | — | — | CN | claimed |
| EP-0233656-A1 | Microbial esterase and process for the preparation of 2-arylpropionic acids | GIST-BROCADES N.V. (NL) | 1987-08-26 | — | — | EP | claimed |
| EP-0205215-A2 | Process for the preparation of 2-arylpropionic acids | GIST-BROCADES N.V. (NL) | 1986-12-17 | — | — | EP | claimed |
| US-4279926-A | PHENYL ALKANOIC ACID SALT OF AN AMINO ACID | SPA-SOCIETA PRODOTTI ANTIBIOTICI S.P.A. (IT) | 1981-07-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252938-A1 | Process for the separation of palladium catalyst from crude reaction mixtures of aryl acetic acids obtained by carbonylation | PDK2, PDHA2, ADH5 | APP 4468/4885PTGS1 2612/4885PTGS2 1669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.