Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5743371 | 0.98 | IDO1 (0.47) | IDO1TDO2OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL5743370 | 0.98 | IDO1 (0.47) | IDO1TDO2OPRM1OPRD1OPRK1 | |
| SCHEMBL8657495 | 0.79 | HDAC4 (0.43) | IDO1TDO2HDAC4HDAC7HDAC5 | |
| SCHEMBL6681577 | 0.79 | IDO1 (0.34) | IDO1TDO2OPRM1OPRD1OPRK1 | |
| SCHEMBL3556521 | 0.78 | HDAC4 (0.42) | IDO1TDO2HDAC4HDAC7HDAC5 | |
| SCHEMBL8724411 | 0.76 | IDO1 (0.52) | IDO1TDO2OPRM1OPRD1OPRK1 | |
| SCHEMBL3254640 | 0.76 | IDO1 (0.52) | IDO1TDO2OPRM1OPRD1OPRK1 | |
| SCHEMBL12568799 | 0.76 | IDO1 (0.52) | IDO1TDO2OPRM1OPRD1OPRK1 | |
| SCHEMBL3296814 | 0.76 | IDO1 (0.52) | IDO1TDO2OPRM1OPRD1OPRK1 | |
| SCHEMBL3253159 | 0.76 | IDO1 (0.52) | IDO1TDO2OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1111162-C | Artemisinin derivatives, method for preparation thereof and pharmaceutical compositions containing the same | SHANGHAI INST OF MATERIAL MEDI (CN) | 2003-06-11 | — | — | CN | disclosed |
| US-6307068-B1 | TREATING OR IN PREVENTING CANCER. | ADIR ET COMPAGNIE (FR) | 2001-10-23 | — | — | US | disclosed |
| CN-1305482-A | Artemisinin derivatives, method for preparation thereof and pharmaceutical compositions containing the same | SHANGHAI INST OF MATERIAL MEDI (CN) | 2001-07-25 | — | — | CN | disclosed |
| EP-1086107-A1 | ARTEMISININ DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999065914-A1 | ARTEMISININ DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SHANGHAI INSTITUTE OF MATERIA MEDICA (CN) | 1999-12-23 | — | — | WO | disclosed |