Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3556521 | 0.81 | HDAC4 (0.42) | HDAC4HDAC7HDAC5IDO1TDO2 | |
| SCHEMBL2162950 | 0.79 | TSHR (0.57) | HDAC4HDAC7HDAC5IDO1TDO2 | |
| SCHEMBL28241554 | 0.79 | TRPA1 (0.57) | HDAC4HDAC7HDAC5IDO1TDO2 | |
| SCHEMBL31377021 | 0.79 | HDAC4 (0.41) | HDAC4HDAC7HDAC5IDO1TDO2 | |
| SCHEMBL2339913 | 0.79 | HDAC4 (0.41) | HDAC4HDAC7HDAC5IDO1TDO2 | |
| SCHEMBL7860964 | 0.79 | IDO1 (0.44) | HDAC4HDAC7HDAC5IDO1TDO2 | |
| SCHEMBL16957359 | 0.79 | HDAC4 (0.41) | HDAC4HDAC7HDAC5IDO1TDO2 | |
| Hydrochloric Acid SCHEMBL5743370 | 0.78 | IDO1 (0.47) | HDAC4HDAC7HDAC5IDO1TDO2 | |
| Hydrochloric Acid SCHEMBL5743371 | 0.78 | IDO1 (0.47) | HDAC4HDAC7HDAC5IDO1TDO2 | |
| SCHEMBL17187573 | 0.77 | CES2 (0.35) | IDO1TDO2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172272-B1 | MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION | MILLIKEN & CO (US) | 2020-11-25 | — | — | EP | disclosed |
| WO-2016014122-A1 | MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION | MILLIKEN & COMPANY (US) | 2016-01-28 | — | — | WO | disclosed |
| EP-0714893-B1 | 2-substituted benzothiazole derivatives useful in the treatment of diabetic complications | GRELAN PHARMACEUTICAL CO (JP) | 1998-10-21 | — | — | EP | disclosed |
| US-5700819-A | ALDOSE REDUCTASE ENZYME INHIBITOR | GRELAN PHARMACEUTICAL CO., LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| EP-0714893-A1 | 2-substituted benzothiazole derivatives useful in the treatment of diabetic complications | GRELAN PHARMACEUTICAL CO., LTD. (JP) | 1996-06-05 | — | — | EP | disclosed |