Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GMPS | P49915 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 2/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.42 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.41 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.41 |
| ▸ | GAPDH | P04406 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28283954 | 0.91 | GMPS (0.47) | GMPSADORA3ADORA2APOLBPI4KA | |
| SCHEMBL447209 | 0.87 | ADORA3 (0.48) | GMPSADORA3ADORA2APOLBPI4KA | |
| SCHEMBL1434125 | 0.85 | ADORA3 (0.48) | GMPSADORA3ADORA2APOLBPI4KA | |
| SCHEMBL29639535 | 0.84 | ADORA3 (0.54) | GMPSADORA3ADORA2APOLBPI4KA | |
| SCHEMBL2270714 | 0.84 | ADORA3 (0.54) | GMPSADORA3ADORA2APOLBPI4KA | |
| SCHEMBL6828797 | 0.81 | ADORA3 (0.53) | GMPSADORA3ADORA2APOLBPI4KA | |
| SCHEMBL10786319 | 0.80 | ADORA3 (0.52) | GMPSADORA3ADORA2APOLBPI4KA | |
| SCHEMBL2534138 | 0.80 | ADORA3 (0.52) | GMPSADORA3ADORA2APOLBPI4KA | |
| Psicofuranine SCHEMBL691065 | 0.80 | GMPS (0.61) | GMPSADORA3ADORA2APOLBPI4KA | |
| Psicofuranine SCHEMBL9389898 | 0.80 | GMPS (0.61) | GMPSADORA3ADORA2APOLBPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303619-B1 | BLOCKING VASOCONSTRICTIVE RESPONSE INDUCED THROUGH ADENOSINE ACTIVATION OF THE A.SUB.3 ADENOSINE RECEPTOR SUBTYPE, COMPRISING ADMINISTERING XANTHINE DERIVATIVE TO MAMMAL | UNIVERSITY OF VIRGINIA | 2001-10-16 | — | — | US | disclosed |
| US-5817760-A | MAMMALIAN CELL MEMBRANES | MERCK & CO., INC. (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0689405-A4 | METHODS FOR PROTECTING TISSUES AND ORGANS FROM ISCHEMIC DAMAGE | GENSIA INC (US) | 1996-09-11 | — | — | EP | disclosed |
| EP-0689405-A1 | METHODS FOR PROTECTING TISSUES AND ORGANS FROM ISCHEMIC DAMAGE | GENSIA, INC. (US) | 1996-01-03 | — | — | EP | disclosed |
| WO-1995011681-A1 | HUMAN ADENOSINE RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1995-05-04 | — | — | WO | disclosed |
| WO-1994021195-A1 | METHODS FOR PROTECTING TISSUES AND ORGANS FROM ISCHEMIC DAMAGE | GENSIA, INC. (US) | 1994-09-29 | — | — | WO | disclosed |