Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.64 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.64 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Naphthylacetic Acid SCHEMBL238445 | 0.96 | NR1H4 (0.71) | NR1H4PTGS1AKR1C3AKR1C2AKR1B1 | |
| 2-Naphthylacetic Acid SCHEMBL29366514 | 0.96 | NR1H4 (0.71) | NR1H4PTGS1AKR1C3AKR1C2AKR1B1 | |
| 2-Naphthylacetic Acid SCHEMBL28641469 | 0.96 | NR1H4 (0.71) | NR1H4PTGS1AKR1C3AKR1C2AKR1B1 | |
| 2-Naphthylacetic Acid SCHEMBL30493868 | 0.96 | NR1H4 (0.71) | NR1H4PTGS1AKR1C3AKR1C2AKR1B1 | |
| 2-Naphthylacetic Acid SCHEMBL23302248 | 0.94 | NR1H4 (0.65) | NR1H4PTGS1AKR1C3AKR1C2AKR1B1 | |
| 2-Naphthylacetic Acid SCHEMBL11045683 | 0.94 | NR1H4 (0.69) | NR1H4PTGS1AKR1C3AKR1C2AKR1B1 | |
| 2-Naphthylacetic Acid SCHEMBL10453180 | 0.94 | NR1H4 (0.69) | NR1H4PTGS1AKR1C3AKR1C2AKR1B1 | |
| 2-Naphthylacetic Acid SCHEMBL11437704 | 0.94 | NR1H4 (0.69) | NR1H4PTGS1AKR1C3AKR1C2AKR1B1 | |
| 2-Naphthylacetic Acid SCHEMBL8987218 | 0.93 | PTGS1 (0.70) | NR1H4PTGS1AKR1C3AKR1C2AKR1B1 | |
| 2-Naphthylacetic Acid SCHEMBL11542553 | 0.93 | NR1H4 (0.63) | NR1H4PTGS1AKR1C3AKR1C2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300499-B1 | α1-adrenergic receptor antagonists | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2001-10-09 | — | — | US | disclosed |