Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778596 | 0.85 | GRIN2B (0.38) | L3MBTL1POLBNPC1MEN1CYP1A2 | |
| SCHEMBL6815084 | 0.78 | NPC1 (0.50) | KDM4EL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL6815081 | 0.78 | NPC1 (0.50) | KDM4EL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL7569694 | 0.76 | MAOB (0.38) | KDM4EL3MBTL1POLBMAOBNPC1 | |
| SCHEMBL6810853 | 0.75 | KDM4E (0.57) | PPARGPPARAKDM4EMAOAMAOB | |
| SCHEMBL7868713 | 0.72 | MAOB (0.46) | KDM4EPOLBMAOBNPC1RAB9A | |
| SCHEMBL7846221 | 0.70 | KMT2A (0.43) | PPARGPPARAPOLBMAOBMEN1 | |
| SCHEMBL8449043 | 0.70 | PPARG (0.43) | PPARGPPARAL3MBTL1NPC1RAB9A | |
| SCHEMBL7862677 | 0.70 | SLC6A4 (0.36) | MAOAMAOBNPC1RAB9AALDH1A1 | |
| SCHEMBL7571037 | 0.68 | HIF1A (0.35) | KDM4EL3MBTL1POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137632-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034238-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |