Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868713 | 0.85 | MAOB (0.46) | KMT2AMEN1NPSR1MAOBPOLB | |
| SCHEMBL29778306 | 0.83 | KMT2A (0.57) | KMT2AMEN1NPSR1GAAPOLB | |
| SCHEMBL6819302 | 0.83 | KMT2A (0.57) | KMT2AMEN1NPSR1GAAPOLB | |
| SCHEMBL6819739 | 0.83 | KMT2A (0.57) | KMT2AMEN1NPSR1GAAPOLB | |
| SCHEMBL7569529 | 0.77 | IDO1 (0.53) | KMT2AMEN1GAAMAOBGRIN2B | |
| SCHEMBL7575928 | 0.77 | VNN1 (0.37) | KMT2AMEN1NPSR1GAAPOLB | |
| SCHEMBL7784388 | 0.71 | NPFFR2 (0.37) | KMT2AMEN1PPARGPPARAGAA | |
| SCHEMBL2056188 | 0.71 | CES2 (0.45) | KMT2AMEN1PPARGPPARAMAOB | |
| SCHEMBL6816545 | 0.71 | CES2 (0.45) | KMT2AMEN1PPARGPPARAMAOB | |
| SCHEMBL26716488 | 0.71 | KMT2A (0.57) | KMT2AMEN1NPSR1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137645-A2 | ALPHA-METHYLBENZYL-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| EP-1137647-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034260-A2 | ALPHA-METHYLBENZYL-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |
| WO-2000034268-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |