SCHEMBL7861569

SCHEMBL7861569

Nc1cc(Sc2ccc(O)cc2)c(N)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 4/20 0.63
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
MCL1 Q07820 4/20 0.50
MAPT P10636 3/20 0.50
THRB P10828 2/20 0.50
PKM P14618 2/20 0.50
MAPK1 P28482 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
GRK6 P43250 1/20 0.50
KDM4E B2RXH2 1/20 0.50
USP2 O75604 1/20 0.50
POLB P06746 3/20 0.45
CSNK1A1 P48729 2/20 0.45
CSNK1D P48730 2/20 0.45
CSNK1G1 Q9HCP0 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
PABPC1 P11940 1/20 0.45
HPGD P15428 1/20 0.45
BLM P54132 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8092263 0.88 ADORA2A (0.80) ADORA2AMEN1KMT2AMCL1MAPT
SCHEMBL11688620 0.87 STAT3 (0.53) ADORA2AMEN1KMT2AMCL1MAPT
SCHEMBL11287107 0.81 ADORA2A (0.67) ADORA2AMEN1KMT2AMCL1MAPT
SCHEMBL10898930 0.81 ADORA2A (0.67) ADORA2AMEN1KMT2AMCL1MAPT
SCHEMBL8731432 0.80 ADORA2A (0.76) ADORA2AMEN1KMT2AMCL1MAPT
SCHEMBL9581277 0.79 ADORA2A (0.51) ADORA2AMEN1KMT2AMCL1MAPT
SCHEMBL13944330 0.78 ADORA2A (1.00) ADORA2AMEN1KMT2AMCL1MAPT
SCHEMBL11692874 0.77 ADORA2A (0.59) ADORA2AMEN1KMT2AMCL1MAPT
SCHEMBL11119572 0.76 ADORA2A (0.60) ADORA2AMEN1KMT2AMCL1MAPT
SCHEMBL13320761 0.75 GRK6 (0.57) ADORA2AMEN1KMT2AMCL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6306550-B1 Color filters MITSUI CHEMICALS, INC. (JP) 2001-10-23 US disclosed
US-5948597-A PHTHALOQUINONE DYES MITSUI CHEMICALS, INC. (JP) 1999-09-07 US disclosed
US-5789137-A PHTHALOCYANINE DYE MITSUI CHEMICALS, INC. (JP) 1998-08-04 US disclosed
EP-0832942-A2 Dyes for color filters, photosensitive resist resin compositions containing the same, and color filters MITSUI TOATSU CHEMICALS, INC. (JP) 1998-04-01 EP disclosed
US-5578419-A Dyes for color filters, and photosensitive resist resin composition containing the same MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-11-26 US disclosed
EP-0546856-A2 Dyes for color filters, photosensitive resist resin compositions containing the same, and color filters MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-06-16 EP disclosed