SCHEMBL8092263

SCHEMBL8092263

Nc1cc(Sc2ccccc2)c(N)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 5/20 0.80
MEN1 O00255 6/20 0.55
KMT2A Q03164 6/20 0.55
MAPT P10636 5/20 0.55
MAPK1 P28482 3/20 0.55
MCL1 Q07820 3/20 0.55
KDM4E B2RXH2 2/20 0.55
THRB P10828 2/20 0.55
NPSR1 Q6W5P4 2/20 0.55
USP2 O75604 1/20 0.55
PKM P14618 1/20 0.55
GRK6 P43250 1/20 0.51
MAOA P21397 2/20 0.50
CSNK1A1 P48729 2/20 0.50
CSNK1D P48730 2/20 0.50
CSNK1G1 Q9HCP0 2/20 0.50
FGR P09769 1/20 0.50
PIM1 P11309 1/20 0.50
DYRK1A Q13627 1/20 0.50
HIPK2 Q9H2X6 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11287107 0.92 ADORA2A (0.67) ADORA2AMEN1KMT2AMAPTMAPK1
SCHEMBL10898930 0.92 ADORA2A (0.67) ADORA2AMEN1KMT2AMAPTMAPK1
SCHEMBL13944330 0.89 ADORA2A (1.00) ADORA2AMEN1KMT2AMAPTMAPK1
SCHEMBL7861569 0.88 ADORA2A (0.63) ADORA2AMEN1KMT2AMAPTMAPK1
SCHEMBL8731432 0.85 ADORA2A (0.76) ADORA2AMEN1KMT2AMAPTMAPK1
SCHEMBL9846550 0.81 ADORA2A (0.65) ADORA2AMEN1KMT2AMAPTMAPK1
SCHEMBL8092232 0.80 ADORA2A (0.68) ADORA2AP2RY4P2RY12P2RY2P2RY1
SCHEMBL9163354 0.79 ADORA2A (0.76) ADORA2AMEN1KMT2AMAPTMAPK1
SCHEMBL13320761 0.77 GRK6 (0.57) ADORA2AMEN1KMT2AMAPTMAPK1
SCHEMBL11688620 0.77 STAT3 (0.53) ADORA2AMEN1KMT2AMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6051360-A A REACTION PRODUCT OF A CHROMOPHORIC NUCLEUS AND A BISPHENOL; EXCELLENT SOLUBILITY IN SOLVENTS AND BINDER RESINS; COLOR FILTERS FOR DISPLAY DEVICES SUCH AS LIQUID CRYSTAL TELEVISION AND COLOR SEPARATION FILTERS FOR IMAGE PICKUP TUBES MITSUI CHEMICALS, INC. (JP) 2000-04-18 US disclosed
EP-0633296-B1 Novel dyestuffs and their use MITSUI CHEMICALS INC (JP) 1999-10-13 EP disclosed
US-5773172-A SOLVENT AND BINDER SOLUBILITY MITSUI TOATSU CHEMICALS, INC. (JP) 1998-06-30 US disclosed
EP-0564237-B1 Preparation of color filter and photo-setting resin therefor MITSUI TOATSU CHEMICALS (JP) 1998-03-11 EP disclosed
US-5482804-A Resin composition for color filter MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-01-09 US disclosed
EP-0633296-A1 Novel dyestuffs and their use MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-01-11 EP disclosed
EP-0564237-A2 Preparation of color filter and photo-setting resin therefor MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-10-06 EP disclosed