Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 15/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7865314 | 0.88 | FDPS (0.46) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL7865374 | 0.87 | FDPS (0.49) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL7861782 | 0.84 | FDPS (0.45) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL7855070 | 0.83 | FDPS (0.44) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL7861882 | 0.81 | FDPS (0.47) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL7862907 | 0.71 | FDPS (0.47) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL6669236 | 0.70 | FDPS (0.63) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL7862033 | 0.70 | FDPS (0.50) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL8050464 | 0.70 | FDPS (0.68) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL7862011 | 0.70 | FDPS (0.40) | FDPSPDE3ALMNAADRB3PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121366-A1 | PRODRUGS OF PHOSPHOROUS-CONTAINING PHARMACEUTICALS | MEDIVIR AB (SE) | 2001-08-08 | — | — | EP | disclosed |
| WO-1999051613-A1 | PRODRUGS OF PHOSPHOROUS-CONTAINING PHARMACEUTICALS | MEDIVIR AB (SE) | 1999-10-14 | — | — | WO | disclosed |