SCHEMBL7861936

SCHEMBL7861936

O=P(O)(O)OC[C@H](O)[C@@H](O)[C@H](O)CO.[CaH2].[CaH2]

nearest known ligand 0.72

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PGD P52209 3/20 0.52
MPI P34949 1/20 0.52
PGK1 P00558 1/20 0.45
PGK2 P07205 1/20 0.45
LMNA P02545 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL638724 0.98 PGD (0.53) PGDMPIPGK1PGK2LMNA
SCHEMBL28129954 0.98 PGD (0.53) PGDMPIPGK1PGK2LMNA
Ribitol SCHEMBL28092351 0.98 PGD (0.53) PGDMPIPGK1PGK2LMNA
SCHEMBL21610 0.98 PGD (0.53) PGDMPIPGK1PGK2LMNA
SCHEMBL2767073 0.98 PGD (0.53) PGDMPIPGK1PGK2LMNA
SCHEMBL468450 0.98 PGD (0.53) PGDMPIPGK1PGK2LMNA
SCHEMBL630930 0.98 PGD (0.53) PGDMPIPGK1PGK2LMNA
SCHEMBL2766970 0.98 PGD (0.53) PGDMPIPGK1PGK2LMNA
SCHEMBL453487 0.98 PGD (0.53) PGDMPIPGK1PGK2LMNA
SCHEMBL435808 0.98 PGD (0.53) PGDMPIPGK1PGK2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0996436-A4 PHARMACEUTICAL FORMULATIONS CONTAINING POORLY SOLUBLE DRUG SUBSTANCES SANOFI SYNTHELABO (FR) 2001-04-11 EP disclosed
EP-0996436-A1 PHARMACEUTICAL FORMULATIONS CONTAINING POORLY SOLUBLE DRUG SUBSTANCES SANOFI-SYNTHELABO (FR) 2000-05-03 EP disclosed
WO-1998038987-A1 PHARMACEUTICAL FORMULATIONS CONTAINING POORLY SOLUBLE DRUG SUBSTANCES SANOFI-SYNTHELABO (FR) 1998-09-11 WO disclosed