Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | PRF1 | P14222 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3171908 | 0.89 | SMN1; SMN2 (0.35) | KDM4EMAPTNPC1RAB9APKM | |
| SCHEMBL7868663 | 0.88 | PGR (0.33) | DPP4 | |
| SCHEMBL7862021 | 0.88 | KDM4E (0.33) | KDM4EMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL7866859 | 0.88 | KDM4E (0.33) | KDM4EMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL7868657 | 0.88 | DPP4 (0.32) | DPP4 | |
| SCHEMBL7862035 | 0.86 | PGR (0.32) | DPP4 | |
| SCHEMBL3158482 | 0.83 | HTT (0.38) | KDM4EMAPTNPC1RAB9AAPP | |
| SCHEMBL3158527 | 0.82 | HTT (0.39) | KDM4EMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL3166254 | 0.79 | HPGD (0.35) | KDM4EMAPTNPC1ALDH1A1HPGD | |
| SCHEMBL3163518 | 0.76 | MAPT (0.37) | KDM4EMAPTNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6312811-B1 | Photochromic naphtho [2,1-b]pyran compounds containing bithienyl or terthienyl substituents, process for their manufacture, and photochromic materials and articles obtained | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2001-11-06 | — | — | US | disclosed |