SCHEMBL7862064

SCHEMBL7862064

Cc1ccc([Si](O[SiH2])(c2ccc(C)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACHE P22303 6/20 0.42
TDP1 Q9NUW8 3/20 0.42
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ALDH1A1 P00352 3/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
NOTUM Q6P988 1/20 0.31
TSHR P16473 4/20 0.31
AGXT P21549 2/20 0.31
CYP3A4 P08684 1/20 0.31
TEAD4 Q15561 1/20 0.31
LMNA P02545 2/20 0.30
ALOX12 P18054 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3867444 0.76 ACHE (0.44) ACHETDP1MEN1KMT2AALDH1A1
SCHEMBL8955110 0.75 CA1 (0.52) ACHETDP1MEN1KMT2AALDH1A1
SCHEMBL7859080 0.72 ESR1 (0.32) ALDH1A1TSHR
SCHEMBL3873557 0.72 ACHE (0.46) ACHETDP1MEN1KMT2AALDH1A1
SCHEMBL3867374 0.70 ACHE (0.38) ACHETDP1MEN1KMT2AALDH1A1
SCHEMBL4707391 0.69 ACHE (0.36) ACHETDP1MEN1KMT2AALDH1A1
SCHEMBL3482517 0.69 ACHE (0.43) ACHETDP1MEN1KMT2AALDH1A1
SCHEMBL13231686 0.67 ACHE (0.57) ACHETDP1ALDH1A1CA1CA2
SCHEMBL4073452 0.67 ACHE (0.57) ACHETDP1ALDH1A1CA1CA2
SCHEMBL987122 0.65 ACHE (0.53) ACHETDP1ALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5034309-A Used for forming a recording layer HITACHI CHEMICAL CO., LTD. (JP) 1991-07-23 US claimed
EP-0527454-B1 Information recording medium having recording layer with organic polymer and dye contained therein HITACHI CHEMICAL CO LTD (JP) 2001-11-07 EP disclosed
US-5648135-A WRITING, ERASING OPTICAL DISKS; NONTOXIC HITACHI CHEMICAL COMPANY, LTD. (JP) 1997-07-15 US disclosed
US-5484685-A Naphthalocyanine derivatives, production thereof, optical recording medium using the same, and production thereof HITACHI, LTD. (JP) 1996-01-16 US disclosed
EP-0464959-B1 Naphthalocyanine derivatives and production processes thereof, as well as optical information recording media using the derivatives and production processes thereof HITACHI CHEMICAL CO LTD (JP) 1995-12-20 EP disclosed
US-5464673-A Information recording medium having recording layer with organic polymer and dye contained therein HITACHI CHEMICAL CO., LTD. (JP) 1995-11-07 US disclosed
EP-0284370-B1 Naphthalocyanine derivatives and production processes thereof, as well as optical information recording media using the derivatives and production processes thereof HITACHI CHEMICAL CO LTD (JP) 1994-06-22 EP disclosed
EP-0366440-B1 Naphthalocyanine derivatives, production thereof, optical recording medium using the same, and production thereof HITACHI CHEMICAL CO LTD (JP) 1994-06-08 EP disclosed
EP-0357360-B1 Naphthalocyanine derivatives, production thereof and optical recording medium using the same HITACHI CHEMICAL CO LTD (JP) 1994-06-08 EP disclosed
US-5268485-A A 1,3-diiminobenz(f)isoindoline derivative HITACHI CHEMICAL COMPANY, LTD. (JP) 1993-12-07 US disclosed
US-5110968-A NAPHTHALOCYANINE DERIVATIVES, PRODUCTION THEREOF, OPTICAL RECORDING MEDIUM USING THE SAME, AND PRODUCTION THEREOF HITACHI, CHEMICAL COMPANY LTD. (JP) 1992-05-05 US disclosed
EP-0464959-A2 Naphthalocyanine derivatives and production processes thereof, as well as optical information recording media using the derivatives and production processes thereof Hitachi Chemical Co., Ltd. (JP) 1992-01-08 EP disclosed
US-5075203-A Containing sulfone groups; absorbers of laser beams HITACHI CHEMICAL COMPANY, LTD. (JP) 1991-12-24 US disclosed
US-5039600-A Solubility in organic solvents, absorption of semiconductor laser light HITACHI CHEMICAL COMPANY, LTD. (JP) 1991-08-13 US disclosed
US-5034309-A Used for forming a recording layer HITACHI CHEMICAL CO., LTD. (JP) 1991-07-23 US disclosed
EP-0378336-A1 Naphthalocyanine derivatives, production thereof, optical recording medium using the same, and production thereof Hitachi Chemical Co., Ltd. (JP) 1990-07-18 EP disclosed
EP-0366440-A2 Naphthalocyanine derivatives, production thereof, optical recording medium using the same, and production thereof Hitachi Chemical Co., Ltd. (JP) 1990-05-02 EP disclosed
EP-0357360-A2 Naphthalocyanine derivatives, production thereof and optical recording medium using the same Hitachi Chemical Co., Ltd. (JP) 1990-03-07 EP disclosed
EP-0296876-A2 Naphthalocyanine derivatives and their use in optical recording medium Hitachi Chemical Co., Ltd. (JP) 1988-12-28 EP disclosed
EP-0284370-A2 Naphthalocyanine derivatives and production processes thereof, as well as optical information recording media using the derivatives and production processes thereof Hitachi Chemical Co., Ltd. (JP) 1988-09-28 EP disclosed