Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | AOC2 | O75106 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22656552 | 0.90 | POLB (0.50) | MAPTNPSR1SMN1; SMN2MEN1LMNA | |
| SCHEMBL28879762 | 0.86 | ALDH1A1 (0.47) | NOTUMMAPTNPSR1SMN1; SMN2MEN1 | |
| SCHEMBL19423149 | 0.83 | SMN1; SMN2 (0.62) | MAPTNPSR1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL24571526 | 0.82 | DDB1 (0.46) | NOTUMMAPTNPSR1SMN1; SMN2MEN1 | |
| SCHEMBL14499049 | 0.82 | NOTUM (0.62) | NOTUMMAPTNPSR1SMN1; SMN2MEN1 | |
| SCHEMBL9644169 | 0.82 | MAPT (0.53) | MAPTNPSR1SMN1; SMN2MEN1LMNA | |
| SCHEMBL8372903 | 0.82 | NPSR1 (0.45) | MAPTNPSR1SMN1; SMN2MEN1LMNA | |
| SCHEMBL12145899 | 0.82 | POLB (0.44) | MAPTNPSR1SMN1; SMN2MEN1LMNA | |
| SCHEMBL10257400 | 0.82 | NPSR1 (0.55) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL14277707 | 0.82 | GRM4 (0.51) | MAPTNPSR1SMN1; SMN2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9056862-B2 | Thioxothiazolidine derivative having Ras function inhibitory effect | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2015-06-16 | — | — | US | disclosed |
| US-9056862-B2 | Thioxothiazolidine derivative having Ras function inhibitory effect | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2015-06-16 | — | — | US | disclosed |
| US-20140194412-A1 | THIOXOTHIAZOLIDINE DERIVATIVE HAVING RAS FUNCTION INHIBITORY EFFECT | KNC LABORATORIES CO., LTD. (JP) | 2014-07-10 | — | — | US | disclosed |
| US-20140194412-A1 | THIOXOTHIAZOLIDINE DERIVATIVE HAVING RAS FUNCTION INHIBITORY EFFECT | KNC LABORATORIES CO., LTD. (JP) | 2014-07-10 | — | — | US | disclosed |
| EP-0972761-B1 | Sulfonium salt and its manufacturing method | KOREA KUMHO PETROCHEM CO LTD (KR) | 2001-12-12 | — | — | EP | disclosed |
| US-6111143-A | BY ONE-STEP REACTION BETWEEN SULFOXIDE COMPOUND AND AROMATIC COMPOUND IN PRESENCE OF PERFLUOROALKANESULFONIC ANHYDRIDE; USE AS POLYMERIZATION PHOTOINITIATOR, OR PHOTOACID GENERATOR LEAVING THE PROTECTION GROUPS OF ORGANIC COMPOUNDS | KOREA KUMBO PETROCHEMICAL CO., LTD. (KR) | 2000-08-29 | — | — | US | disclosed |
| EP-0972761-A1 | Sulfonium salt and its manufacturing method | Korea Kumho Petrochemical Co. Ltd. (KR) | 2000-01-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140194412-A1 | THIOXOTHIAZOLIDINE DERIVATIVE HAVING RAS FUNCTION INHIBITORY EFFECT | KRAS, NRAS, RASSF5 | NOTUM 3670/4885MAPT 3612/4885NPSR1 2607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.