Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7874113 | 0.99 | SMN1; SMN2 (0.65) | KDRSMN1; SMN2MAPTGFERGAA | |
| SCHEMBL7869899 | 0.80 | SMN1; SMN2 (0.74) | SMN1; SMN2MAPTGFERGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL7862098 | 0.79 | SMN1; SMN2 (0.72) | SMN1; SMN2MAPTGFERGAAALDH1A1 | |
| SCHEMBL7868780 | 0.78 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTGFERGAAALDH1A1 | |
| SCHEMBL7866953 | 0.78 | SMN1; SMN2 (0.67) | SMN1; SMN2MAPTGFERGAAALDH1A1 | |
| SCHEMBL8015894 | 0.78 | SMN1; SMN2 (0.70) | SMN1; SMN2MAPTGFERGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL7862199 | 0.77 | SMN1; SMN2 (0.66) | SMN1; SMN2MAPTGFERGAAALDH1A1 | |
| SCHEMBL5998386 | 0.77 | JAK2 (0.59) | KDRHRH3 | |
| SCHEMBL4968829 | 0.77 | GCGR (0.69) | KDRHRH3MCHR1 | |
| SCHEMBL7866981 | 0.76 | SMN1; SMN2 (0.65) | SMN1; SMN2MAPTGFERGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300368-B1 | FOR THERAPY OF ATRIAL ARRHYTHMIA | MITSUI CHEMICALS, INC. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0968999-A1 | Anilide derivatives and antiarrhythmic agents containing the same | Mitsui Chemicals, Inc. (JP) | 2000-01-05 | — | — | EP | disclosed |