Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.59 |
| ▸ | KDR | P35968 | 4/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.52 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4967552 | 0.83 | KDR (0.59) | GCGRMCHR1KDRHRH3EPHX2 | |
| SCHEMBL4969245 | 0.81 | MCHR1 (0.70) | GCGRMEN1KMT2AMCHR1KDR | |
| Oxalic Acid SCHEMBL5449181 | 0.78 | MEN1 (0.54) | GCGRMEN1KMT2AHRH3EPHX2 | |
| SCHEMBL7869890 | 0.78 | LTA4H (0.61) | MEN1KMT2AMCHR1KDRHRH3 | |
| SCHEMBL10960859 | 0.78 | KMT2A (1.00) | MEN1KMT2ADEGS1NPC1RAB9A | |
| SCHEMBL13438292 | 0.77 | GCGR (0.64) | GCGRMEN1KMT2AHRH3BCHE | |
| SCHEMBL2111310 | 0.77 | GCGR (0.64) | GCGRBCHE | |
| SCHEMBL7450714 | 0.77 | GCGR (0.70) | GCGRHRH3BCHEKCNH2PSMB1 | |
| SCHEMBL3581039 | 0.77 | GCGR (0.64) | GCGRMEN1KMT2AHRH3BCHE | |
| SCHEMBL13438290 | 0.77 | GCGR (0.64) | GCGRMEN1KMT2AHRH3BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954670-A2 | NUCLEAR RECEPTOR BINDING AGENTS | GTX Inc. (US) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007062230-A2 | NUCLEAR RECEPTOR BINDING AGENTS | GTX, INC. (US) | 2007-05-31 | — | — | WO | disclosed |