Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCPS | Q96C86 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL62601 | 1.00 | DCPS (0.36) | DCPSADORA2APDPK1GDACASP1 | |
| Bromide SCHEMBL62599 | 1.00 | DCPS (0.36) | DCPSADORA2APDPK1GDACASP1 | |
| SCHEMBL33841 | 0.96 | DCPS (0.38) | DCPSADORA2APDPK1GDACASP1 | |
| Hydrochloric Acid SCHEMBL19858969 | 0.92 | DCPS (0.36) | DCPSADORA2APDPK1GDACASP1 | |
| Hydrochloric Acid SCHEMBL63511 | 0.92 | DCPS (0.36) | DCPSADORA2APDPK1GDACASP1 | |
| Hydrochloric Acid SCHEMBL19858968 | 0.92 | DCPS (0.36) | DCPSADORA2APDPK1GDACASP1 | |
| Hydrochloric Acid SCHEMBL1450085 | 0.92 | DCPS (0.36) | DCPSADORA2APDPK1GDACASP1 | |
| SCHEMBL6944829 | 0.81 | PIK3CG (0.31) | DCPSADORA2APDPK1 | |
| SCHEMBL6943391 | 0.78 | CYP1A2 (0.31) | DCPSADORA2APDPK1CASP1 | |
| Sulfuric Acid SCHEMBL20815930 | 0.78 | PDPK1 (0.34) | DCPSADORA2APDPK1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144412-A1 | IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | K.U. Leuven Research & Development (BE) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000039129-A1 | IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2000-07-06 | — | — | WO | disclosed |