Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 19/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862313 | 0.85 | CYP19A1 (0.46) | CYP19A1 | |
| SCHEMBL23768679 | 0.84 | CYP19A1 (0.45) | CYP19A1 | |
| SCHEMBL10943585 | 0.81 | CYP19A1 (0.45) | CYP19A1 | |
| SCHEMBL7864624 | 0.80 | CYP19A1 (0.42) | CYP19A1CYP2C19 | |
| SCHEMBL3452968 | 0.77 | ESR1 (0.43) | CYP19A1ESR1CHRM2ACHESLC6A2 | |
| SCHEMBL7861153 | 0.77 | CYP19A1 (0.66) | CYP19A1ESR1CHRM2ACHESLC6A2 | |
| SCHEMBL9019877 | 0.77 | PGR (0.46) | CYP19A1 | |
| SCHEMBL20851681 | 0.74 | CYP19A1 (0.45) | CYP19A1ESR1CHRM2ACHESLC6A2 | |
| SCHEMBL3183804 | 0.74 | ESR1 (0.43) | CYP19A1ESR1CHRM2ACHESLC6A2 | |
| SCHEMBL20851685 | 0.74 | ESR1 (0.43) | CYP19A1ESR1CHRM2ACHESLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709394-B1 | Steroids with a 17-spiromethylene lactone or lactol group | AKZO NOBEL NV (NL) | 2001-01-31 | — | — | EP | disclosed |
| US-5741786-A | PROGESTATIONAL ACTIVITY, USED AS CONTRACEPTIVES | AKZO NOBEL N.V. (NL) | 1998-04-21 | — | — | US | disclosed |
| EP-0709394-A2 | Steroids with a 17-spiromethylene lactone or lactol group | Akzo Nobel N.V. (NL) | 1996-05-01 | — | — | EP | disclosed |