Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860205 | 0.86 | MEN1 (0.42) | TSHRMEN1KMT2AALDH1A1GLA | |
| SCHEMBL2485564 | 0.82 | MEN1 (0.45) | TSHRMEN1KMT2AALDH1A1GLA | |
| SCHEMBL1830325 | 0.81 | MEN1 (0.44) | TSHRMEN1KMT2AALDH1A1GLA | |
| SCHEMBL5785897 | 0.81 | MEN1 (0.44) | TSHRMEN1KMT2AALDH1A1GLA | |
| SCHEMBL321543 | 0.80 | MEN1 (0.45) | TSHRMEN1KMT2AALDH1A1GLA | |
| SCHEMBL7559771 | 0.80 | MEN1 (0.50) | TSHRMEN1KMT2AALDH1A1GLA | |
| SCHEMBL7750180 | 0.80 | MEN1 (0.45) | TSHRMEN1KMT2AALDH1A1GLA | |
| SCHEMBL7556725 | 0.78 | KMT2A (0.43) | TSHRMEN1KMT2AALDH1A1GLA | |
| SCHEMBL7865102 | 0.78 | MEN1 (0.38) | MEN1KMT2ATP53KDM5ACYP1A2 | |
| SCHEMBL18751640 | 0.78 | TP53 (0.51) | TSHRMEN1KMT2AALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097139-A1 | QUINOLINE DERIVATIVES | Active Biotech AB (SE) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000003992-A1 | QUINOLINE DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2000-01-27 | — | — | WO | disclosed |