Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.48 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | EDNRB | P24530 | 2/20 | 0.41 |
| ▸ | EDNRA | P25101 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 5/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1530402 | 1.00 | CAMK2A (0.48) | CAMK2ASRD5A1MAP4K4PDE5ASRD5A2 | |
| SCHEMBL15897038 | 0.90 | CAMK2A (0.52) | CAMK2ASRD5A1MAP4K4PDE5ASRD5A2 | |
| SCHEMBL10469026 | 0.86 | FABP4 (0.43) | CAMK2ASRD5A1SRD5A2EDNRBEDNRA | |
| SCHEMBL17361500 | 0.85 | SRD5A1 (0.43) | CAMK2ASRD5A1MAP4K4PDE5ASRD5A2 | |
| SCHEMBL12501482 | 0.85 | SRD5A1 (0.43) | CAMK2ASRD5A1MAP4K4PDE5ASRD5A2 | |
| SCHEMBL12501609 | 0.85 | SRD5A1 (0.43) | CAMK2ASRD5A1MAP4K4PDE5ASRD5A2 | |
| SCHEMBL6772814 | 0.84 | CAMK2A (0.44) | CAMK2ASRD5A1MAP4K4PDE5ASRD5A2 | |
| SCHEMBL22039443 | 0.83 | CAMK2A (0.43) | CAMK2ASRD5A1SRD5A2EDNRBEDNRA | |
| SCHEMBL22040771 | 0.83 | CAMK2A (0.43) | CAMK2ASRD5A1SRD5A2EDNRBEDNRA | |
| SCHEMBL23997446 | 0.81 | SRD5A1 (0.44) | CAMK2ASRD5A1SRD5A2TRPV1PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807101-B1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | UPJOHN CO (US) | 2001-06-13 | — | — | EP | disclosed |
| US-5936000-A | 2-aminoindans as selective dopamine D3 ligands | PHARMACIA & UPJOHN COMPANY (US) | 1999-08-10 | — | — | US | disclosed |
| WO-1996023760-A1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 1996-08-08 | — | — | WO | disclosed |