Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410245 | 0.84 | KMT2A (0.50) | TPSAB1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL29673223 | 0.84 | KMT2A (0.50) | TPSAB1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL7862501 | 0.84 | NPC1 (0.41) | TPSAB1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL7861299 | 0.84 | NPC1 (0.44) | ALDH1A1MAPTKMT2ALMNAKDM4E | |
| Hydrochloric Acid SCHEMBL5957935 | 0.82 | KMT2A (0.53) | TPSAB1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL5504129 | 0.82 | KMT2A (0.47) | TPSAB1ALDH1A1MAPTKMT2ALMNA | |
| Hydrochloric Acid SCHEMBL5957846 | 0.80 | KMT2A (0.50) | TPSAB1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL5957796 | 0.80 | KMT2A (0.46) | TPSAB1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL7861297 | 0.80 | EGFR (0.43) | TPSAB1ALDH1A1KDM4ENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6259121 | 0.79 | KMT2A (0.48) | TPSAB1ALDH1A1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807101-B1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | UPJOHN CO (US) | 2001-06-13 | — | — | EP | disclosed |
| US-5936000-A | 2-aminoindans as selective dopamine D3 ligands | PHARMACIA & UPJOHN COMPANY (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0807101-A1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996023760-A1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 1996-08-08 | — | — | WO | disclosed |