Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2450359 | 0.93 | DRD4 (0.46) | DRD2DRD4DRD3KCNH2ALDH1A1 | |
| SCHEMBL6539339 | 0.86 | KCNA3 (0.59) | DRD2DRD4DRD3KCNH2ALDH1A1 | |
| SCHEMBL6539543 | 0.84 | KCNA3 (0.61) | DRD2DRD4DRD3KCNH2ALDH1A1 | |
| SCHEMBL2450334 | 0.83 | SCN4A (0.39) | DRD2DRD4DRD3KCNH2 | |
| SCHEMBL2455319 | 0.81 | KCNA3 (0.56) | DRD2DRD4DRD3KCNH2ALDH1A1 | |
| SCHEMBL4629349 | 0.79 | KCNA3 (0.37) | KCNA3 | |
| SCHEMBL2451127 | 0.79 | KCNA3 (0.52) | DRD2DRD4DRD3KCNH2ALDH1A1 | |
| SCHEMBL4827804 | 0.79 | GPR84 (0.47) | — | |
| SCHEMBL30514014 | 0.78 | HRH3 (0.61) | DRD2DRD4DRD3KCNH2HRH3 | |
| SCHEMBL11815991 | 0.78 | HRH3 (0.61) | DRD2DRD4DRD3KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623608-B1 | BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LTD (JP) | 2001-05-30 | — | — | EP | disclosed |
| EP-0623608-A1 | BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1994-11-09 | — | — | EP | disclosed |