Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864502 | 0.84 | TAAR1 (0.48) | SLC6A2SLC6A3GAASLC6A4MAPT | |
| SCHEMBL7115349 | 0.82 | ANPEP (0.48) | SLC6A2SLC6A3SLC6A4KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7864363 | 0.79 | SLC6A2 (0.47) | SLC6A2SLC6A3GAASLC6A4HPGD | |
| SCHEMBL9481333 | 0.77 | SLC6A4 (0.58) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL6566603 | 0.76 | GAA (0.56) | SLC6A2SLC6A3GAADNM1KMT2A | |
| SCHEMBL10585879 | 0.74 | SLC6A2 (0.52) | SLC6A2SLC6A3GAASLC6A4HPGD | |
| SCHEMBL15178160 | 0.74 | SLC6A2 (0.52) | SLC6A2SLC6A3GAASLC6A4HPGD | |
| SCHEMBL4161150 | 0.73 | SLC6A2 (0.61) | SLC6A2SLC6A3SLC6A4ACACBKMT2A | |
| SCHEMBL4158699 | 0.73 | SLC6A2 (0.61) | SLC6A2SLC6A3SLC6A4ACACBKMT2A | |
| SCHEMBL2424315 | 0.73 | SLC6A2 (0.61) | SLC6A2SLC6A3SLC6A4ACACBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144396-A2 | SUBSTITUTED 2-ARYLIMINO HETEROCYCLES AND COMPOSITIONS CONTAINING THEM, FOR USE AS PROGESTERONE RECEPTOR BINDING AGENTS | Bayer Corporation (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000042031-A2 | SUBSTITUTED 2-ARYLIMINO HETEROCYCLES AND COMPOSITIONS CONTAINING THEM, FOR USE AS PROGESTERONE RECEPTOR BINDING AGENTS | BAYER CORPORATION (US) | 2000-07-20 | — | — | WO | disclosed |