Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869926 | 0.88 | P4HTM (0.47) | P4HTMEGFRSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7867824 | 0.88 | P4HTM (0.44) | P4HTMEPHX2EGFRRAB9AKCNH2 | |
| SCHEMBL9574743 | 0.87 | SMN1; SMN2 (0.40) | SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL7867703 | 0.84 | EGFR (0.45) | P4HTMEPHX2EGFRSMN1; SMN2RAB9A | |
| SCHEMBL7870559 | 0.84 | EGFR (0.41) | P4HTMEPHX2EGFRBCL2L1MCL1 | |
| SCHEMBL7870444 | 0.84 | P4HTM (0.46) | P4HTMEPHX2EGFRSMN1; SMN2RAB9A | |
| SCHEMBL7871544 | 0.83 | MCL1 (0.49) | P4HTMBCL2L1MCL1 | |
| SCHEMBL7862692 | 0.83 | EGFR (0.43) | P4HTMEPHX2EGFRSMN1; SMN2RAB9A | |
| SCHEMBL9574842 | 0.82 | EGFR (0.43) | P4HTMEPHX2EGFRSMN1; SMN2RAB9A | |
| SCHEMBL7869460 | 0.82 | EGFR (0.43) | P4HTMEPHX2EGFRSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |