Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 9/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 8/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869459 | 0.92 | MCL1 (0.52) | MCL1BCL2L1P4HTMOPRM1OPRD1 | |
| SCHEMBL7862722 | 0.91 | NPC1 (0.51) | MCL1BCL2L1P4HTM | |
| SCHEMBL7867703 | 0.89 | EGFR (0.45) | P4HTM | |
| SCHEMBL7862692 | 0.87 | EGFR (0.43) | P4HTMOPRM1OPRD1OPRK1 | |
| SCHEMBL7862823 | 0.87 | MCL1 (0.48) | MCL1BCL2L1 | |
| SCHEMBL9574842 | 0.86 | EGFR (0.43) | P4HTM | |
| SCHEMBL8868775 | 0.86 | P4HTM (0.53) | MCL1BCL2L1P4HTM | |
| SCHEMBL7869460 | 0.86 | EGFR (0.43) | P4HTM | |
| SCHEMBL7871550 | 0.86 | NPC1 (0.43) | P4HTMOPRM1OPRD1OPRK1 | |
| SCHEMBL9574776 | 0.85 | ALDH1A1 (0.44) | P4HTMOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |