SCHEMBL7862906 — predicted protein targets

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	FDPS	P14324	16/20	0.44

▸	PDE3A	Q14432	2/20	0.44

▸	GGPS1	O95749	6/20	0.34

▸	LMNA	P02545	1/20	0.33

▸	ADRB3	P13945	1/20	0.33

▸	PDE4D	Q08499	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7862907	0.89	FDPS (0.47)	FDPSPDE3AGGPS1LMNAADRB3
SCHEMBL7862033	0.86	FDPS (0.50)	FDPSPDE3AGGPS1LMNAADRB3
SCHEMBL7855070	0.83	FDPS (0.44)	FDPSPDE3AGGPS1LMNAADRB3
SCHEMBL7860476	0.82	FDPS (0.45)	FDPSPDE3AGGPS1LMNAADRB3
SCHEMBL7861882	0.81	FDPS (0.47)	FDPSPDE3AGGPS1LMNAADRB3
SCHEMBL3738080	0.81	FDPS (0.37)	FDPSPDE3A
SCHEMBL7855065	0.79	FDPS (0.40)	FDPSPDE3ALMNAADRB3PDE4D
SCHEMBL7861872	0.79	FDPS (0.40)	FDPSPDE3ALMNAADRB3PDE4D
SCHEMBL7862915	0.77	FDPS (0.40)	FDPSPDE3ALMNAADRB3PDE4D
SCHEMBL7861919	0.77	FDPS (0.40)	FDPSPDE3ALMNAADRB3PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1121366-A1	PRODRUGS OF PHOSPHOROUS-CONTAINING PHARMACEUTICALS	MEDIVIR AB (SE)	2001-08-08	—	—	EP	disclosed
WO-1999051613-A1	PRODRUGS OF PHOSPHOROUS-CONTAINING PHARMACEUTICALS	MEDIVIR AB (SE)	1999-10-14	—	—	WO	disclosed