Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6722653 | 0.89 | PTGS2 (0.68) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL6513081 | 0.88 | PTGS2 (0.55) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL6728774 | 0.87 | PTGS2 (0.74) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL6721397 | 0.87 | PTGS2 (0.72) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL6514245 | 0.86 | PTGS2 (0.53) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL6723125 | 0.86 | PTGS2 (0.64) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL6722834 | 0.86 | PTGS2 (0.73) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL6512653 | 0.86 | PTGS2 (0.57) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL6721918 | 0.85 | PTGS2 (0.65) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL6514073 | 0.85 | PTGS2 (0.65) | PTGS2PTGS1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086097-A1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER INC. (US) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999064415-A1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 1999-12-16 | — | — | WO | disclosed |