Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | SPHK2 | Q9NRA0 | 5/20 | 0.53 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710392 | 0.91 | CYP3A4 (0.50) | CYP3A4CYP2C19SPHK2SPHK1NPC1 | |
| SCHEMBL12189229 | 0.86 | CYP2C19 (0.72) | CYP3A4CYP2C19NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7856365 | 0.85 | NPSR1 (0.56) | SPHK2SPHK1KMT2AKCNH2HRH3 | |
| SCHEMBL12587132 | 0.80 | CYP3A4 (0.76) | CYP3A4CYP2C19NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7861726 | 0.80 | L3MBTL1 (0.63) | SMN1; SMN2MMP1MMP3MMP7MMP13 | |
| SCHEMBL10726957 | 0.79 | SMN1; SMN2 (0.58) | CYP3A4NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5245752 | 0.78 | MAPT (0.65) | CYP2C19NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL5254341 | 0.78 | CYP3A4 (0.76) | CYP3A4CYP2C19SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL19265264 | 0.78 | CYP3A4 (0.76) | CYP3A4CYP2C19RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL4741603 | 0.78 | CYP2C19 (0.75) | CYP3A4CYP2C19SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861210-B1 | USE OF SULFONAMIDES FOR CONTROLLING BIOFOULING | BUCKMAN LABOR INC (US) | 2001-12-12 | — | — | EP | claimed |
| EP-0861210-A1 | METHODS AND COMPOSITIONS FOR CONTROLLING BIOFOULING USING SULFONAMIDES | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 1998-09-02 | — | — | EP | claimed |
| WO-1997011913-A1 | METHODS AND COMPOSITIONS FOR CONTROLLING BIOFOULING USING SULFONAMIDES | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 1997-04-03 | — | — | WO | claimed |
| EP-0861210-B1 | USE OF SULFONAMIDES FOR CONTROLLING BIOFOULING | BUCKMAN LABOR INC (US) | 2001-12-12 | — | — | EP | disclosed |