SCHEMBL7863529

SCHEMBL7863529

CCO/N=C(C(/C)=N/OCc1ccccc1/C(=N\OC)C(=O)OC)\c1ccc(OC[Si](C)(C)c2ccc(F)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.44
MAOB P27338 2/20 0.31
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7870366 0.92 HIF1A (0.36) HIF1AMAOBPPARGPPARAKDM4E
SCHEMBL8543770 0.84 HIF1A (0.51) HIF1AKDM4ESMN1; SMN2
SCHEMBL7500390 0.80 HIF1A (0.54) HIF1AKDM4ESMN1; SMN2
SCHEMBL7468302 0.79 HIF1A (0.60) HIF1AMAOB
SCHEMBL7870369 0.77 CXCR1 (0.34) PPARGPPARALMNAALDH1A1GAA
SCHEMBL7127228 0.77 HIF1A (0.59) HIF1AKDM4ELMNAALDH1A1SMN1; SMN2
SCHEMBL7127227 0.77 HIF1A (0.59) HIF1AKDM4ELMNAALDH1A1SMN1; SMN2
SCHEMBL7872444 0.77 MAOB (0.40) MAOBPPARGPPARALMNAALDH1A1
SCHEMBL7467513 0.77 MAOB (0.41) HIF1AMAOBLMNA
SCHEMBL7467515 0.77 MAOB (0.41) HIF1AMAOBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313344-B1 PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-11-06 US disclosed
EP-0984923-A1 O-BENZYL OXIME ETHERS AND THEIR USE AS PESTICIDES Novartis AG (CH) 2000-03-15 EP disclosed
WO-1998054125-A1 O-BENZYL OXIME ETHERS AND THEIR USE AS PESTICIDES NOVARTIS AG (CH) 1998-12-03 WO disclosed