Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 19/20 | 0.56 |
| ▸ | PDE4A | P27815 | 12/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 12/20 | 0.56 |
| ▸ | PDE1A | P54750 | 2/20 | 0.52 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7857182 | 0.85 | PDE4B (0.67) | PDE4BPDE4APDE4CPDE4DPDE1A | |
| SCHEMBL7864520 | 0.85 | PDE4B (0.69) | PDE4BPDE4APDE4CPDE4DPDE1A | |
| SCHEMBL7857068 | 0.84 | PDE4B (0.70) | PDE4BPDE4APDE4CPDE4DPDE1A | |
| SCHEMBL7868234 | 0.83 | PDE4B (0.52) | PDE4BPDE4APDE4CPDE4DPDE1A | |
| SCHEMBL11993050 | 0.83 | PDE4B (0.54) | PDE4BPDE4APDE4CPDE4DPDE1A | |
| SCHEMBL11993046 | 0.82 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4DPDE1A | |
| SCHEMBL7995291 | 0.81 | PDE4B (0.75) | PDE4BPDE4APDE4CPDE4DPDE1A | |
| SCHEMBL18595962 | 0.81 | PDE4B (0.71) | PDE4BPDE4APDE4CPDE4DPDE1A | |
| SCHEMBL7862946 | 0.81 | PDE4B (0.55) | PDE4BPDE4APDE4CPDE4DPDE1A | |
| SCHEMBL10172382 | 0.81 | PDE4B (0.69) | PDE4BPDE4APDE4CPDE4DPDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| US-20090291917-A1 | Boron-Containing Small Molecules as Anti-Inflammatory Agents | ANACOR PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291917-A1 | Boron-Containing Small Molecules as Anti-Inflammatory Agents | NFKBIA, LITAF, CD68 | PDE4B 776/4885PDE4A 1019/4885PDE4C 1729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.