Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 7/20 | 0.45 |
| ▸ | CA1 | P00915 | 7/20 | 0.45 |
| ▸ | CA2 | P00918 | 7/20 | 0.45 |
| ▸ | CA9 | Q16790 | 7/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13427968 | 1.00 | HSD17B10 (0.47) | HSD17B10CYP2D6THRBMAPTCYP3A4 | |
| SCHEMBL13402445 | 1.00 | HSD17B10 (0.47) | HSD17B10CYP2D6THRBMAPTCYP3A4 | |
| SCHEMBL25985483 | 1.00 | HSD17B10 (0.47) | HSD17B10CYP2D6THRBMAPTCYP3A4 | |
| SCHEMBL12083311 | 1.00 | HSD17B10 (0.47) | HSD17B10CYP2D6THRBMAPTCYP3A4 | |
| SCHEMBL15494654 | 1.00 | HSD17B10 (0.47) | HSD17B10CYP2D6THRBMAPTCYP3A4 | |
| SCHEMBL10148737 | 1.00 | HSD17B10 (0.47) | HSD17B10CYP2D6THRBMAPTCYP3A4 | |
| SCHEMBL12968777 | 1.00 | HSD17B10 (0.47) | HSD17B10CYP2D6THRBMAPTCYP3A4 | |
| SCHEMBL62522 | 1.00 | HSD17B10 (0.47) | HSD17B10CYP2D6THRBMAPTCYP3A4 | |
| SCHEMBL8602259 | 1.00 | HSD17B10 (0.47) | HSD17B10CYP2D6THRBMAPTCYP3A4 | |
| SCHEMBL7150795 | 0.92 | HSD17B10 (0.46) | HSD17B10CYP2D6THRBMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 572 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11191273-B2 | Methods of making pyranopyrans such as pyranopyran nitrile and methods of using pyranopyrans such as pyranopyran nitrile | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2021-12-07 | — | — | US | claimed |
| EP-2831253-B1 | ENZYMES USEFUL FOR PERACID PRODUCTION | DUPONT US HOLDING LLC (US) | 2021-11-24 | — | — | EP | claimed |
| CN-104988187-B | Production of peracids using enzymes having perhydrolytic activity | 纳幕尔杜邦公司 | 2021-02-05 | — | — | CN | claimed |
| US-8962294-B2 | Perhydrolase variant providing improved specific activity | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-02-24 | — | — | US | claimed |
| US-8956843-B2 | Perhydrolase variant providing improved specific activity | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-02-17 | — | — | US | claimed |
| EP-2831253-A1 | ENZYMES USEFUL FOR PERACID PRODUCTION | E. I. Du Pont de Nemours and Company (US) | 2015-02-04 | — | — | EP | claimed |
| EP-2831251-A1 | ENZYMES USEFUL FOR PERACID PRODUCTION | E. I. Du Pont de Nemours and Company (US) | 2015-02-04 | — | — | EP | claimed |
| EP-2831226-A1 | ENZYMES USEFUL FOR PERACID PRODUCTION | E. I. Du Pont de Nemours and Company (US) | 2015-02-04 | — | — | EP | claimed |
| EP-2831252-A1 | ENZYMES USEFUL FOR PERACID PRODUCTION | E. I. Du Pont de Nemours and Company (US) | 2015-02-04 | — | — | EP | claimed |
| EP-2831250-A1 | ENZYMES USEFUL FOR PERACID PRODUCTION | E. I. Du Pont de Nemours and Company (US) | 2015-02-04 | — | — | EP | claimed |
| US-20080176783-A1 | Production of Peracids Using An Enzyme Having Perhydrolysis Activity | DUPONT US HOLDING, LLC | 2008-07-24 | — | — | US | claimed |
| WO-2008073139-A1 | PRODUCTION OF PERACIDS USING AN ENZYME HAVING PERHYDROLYSIS ACTIVITY | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-06-19 | — | — | WO | claimed |
| US-6673907-B2 | NOVEL SUBSTITUTED TETRACYCLINES WITH MODIFIED ALKYL-AROMATIC RING SUBSTITUTIONS ON THE C-3' AND/OR C-4' OF THE SUGAR MOIETY; CYTOTOXICITY; ANTITUMOR, -CARCINOGENIC AGENTS; MULTIDRUG RESISTANCE | HOUSTON PHARMACEUTICALS, INC. | 2004-01-06 | — | — | US | claimed |
| US-20020137694-A1 | Methods and compositions for the manufacture of C-3' and C-4' anthracycline antibiotics | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-09-26 | — | — | US | claimed |
| EP-1165578-A4 | METHODS AND COMPOSITIONS FOR THE MANUFACTURE OF C-3' AND C-4' ANTHRACYCLINE ANTIBIOTICS | PRIEBE WALDEMAR (US) | 2002-08-28 | — | — | EP | claimed |
| EP-1165578-A2 | METHODS AND COMPOSITIONS FOR THE MANUFACTURE OF C-3' AND C-4' ANTHRACYCLINE ANTIBIOTICS | Priebe, Waldemar (US) | 2002-01-02 | — | — | EP | claimed |
| WO-2000056267-A2 | METHODS AND COMPOSITIONS FOR THE MANUFACTURE OF C-3' AND C-4' ANTHRACYCLINE ANTIBIOTICS | PRIEBE WALDEMAR (US) | 2000-09-28 | — | — | WO | claimed |
| US-5128463-A | Process for the preparation of 2-deoxy sugars | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-07-07 | — | — | US | claimed |
| US-4362720-A | Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2-deoxyglycosides from glycals | CHEMBIOMED LTD. (CA) | 1982-12-07 | — | — | US | claimed |
| US-4195174-A | Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2-deoxyglycosides from glycals | CHEMBIOMED LTD. (CA) | 1980-03-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11191273-B2 | Methods of making pyranopyrans such as pyranopyran nitrile and methods of using pyranopyrans such as pyranopyran nitrile | CBR1, NOX1, NOX3 | HSD17B10 1643/4885CYP2D6 17/4885THRB 2193/4885 |
| US-20020137694-A1 | Methods and compositions for the manufacture of C-3' and C-4' anthracycline antibiotics | HCCS, GALE, BCL3 | HSD17B10 2268/4885CYP2D6 164/4885THRB 4285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.