Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | ANPEP | P15144 | 2/20 | 0.35 |
| ▸ | IL1RN | P18510 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28919129 | 0.96 | PDCD1 (0.37) | PDCD1CD274PRCPHTR7HTR1A | |
| SCHEMBL30229874 | 0.96 | PDCD1 (0.39) | PDCD1CD274PRCPHTR7HTR1A | |
| SCHEMBL1827132 | 0.96 | PDCD1 (0.39) | PDCD1CD274PRCPHTR7HTR1A | |
| SCHEMBL27185392 | 0.95 | PDCD1 (0.38) | PDCD1CD274PRCPHTR7HTR1A | |
| Lithium SCHEMBL6324236 | 0.95 | PDCD1 (0.38) | PDCD1CD274PRCPHTR7HTR1A | |
| SCHEMBL7643421 | 0.95 | PDCD1 (0.38) | PDCD1CD274PRCPHTR7HTR1A | |
| SCHEMBL7863648 | 0.95 | PDCD1 (0.38) | PDCD1CD274PRCPHTR7HTR1A | |
| SCHEMBL6324232 | 0.95 | PDCD1 (0.38) | PDCD1CD274PRCPHTR7HTR1A | |
| Hydrochloric Acid SCHEMBL3693504 | 0.90 | PRCP (0.33) | PDCD1CD274PRCPHTR7HTR1A | |
| SCHEMBL28919128 | 0.90 | PDCD1 (0.35) | PDCD1CD274PRCPHTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112898459-A | Preparation method of spherical modified montmorillonite and preparation method of spherical polyolefin catalyst | 中国石油天然气股份有限公司 | 2021-06-04 | — | — | CN | claimed |
| CN-112898459-A | Preparation method of spherical modified montmorillonite and preparation method of spherical polyolefin catalyst | 中国石油天然气股份有限公司 | 2021-06-04 | — | — | CN | disclosed |
| CN-101855249-B | In-line process for producing plasticized polymers and plasticized polymer blends | EXXONMOBIL RES & ENG CO | 2013-02-13 | — | — | CN | disclosed |
| CN-101568555-B | Process for fluid phase in-line blending of polymers | EXXONMOBIL RES & ENG CO | 2012-11-28 | — | — | CN | disclosed |
| CN-101679533-B | Monomer recycle process for fluid phase in-line blending of polymers | EXXONMOBIL RES & ENG CO | 2012-07-04 | — | — | CN | disclosed |
| CN-101855249-A | In-line process for producing plasticized polymers and plasticized polymer blends | EXXONMOBIL RES & ENG CO | 2010-10-06 | — | — | CN | disclosed |
| CN-101679533-A | Monomer recycle process for fluid phase in-line blending of polymers | EXXONMOBIL RES & ENG CO | 2010-03-24 | — | — | CN | disclosed |
| CN-101568555-A | Process for fluid phase in-line blending of polymers | EXXONMOBIL RES & ENG CO (US) | 2009-10-28 | — | — | CN | disclosed |
| EP-1141034-A2 | BRIDGED METAL COMPLEXES FOR GAS PHASE POLYMERIZATIONS | BP Chemicals Limited (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000020462-A2 | BRIDGED METAL COMPLEXES FOR GAS PHASE POLYMERIZATIONS | BP CHEMICALS LIMITED (GB) | 2000-04-13 | — | — | WO | disclosed |