⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701682 | 0.81 | — | — | |
| SCHEMBL78637 | 0.80 | TSHR (0.35) | — | |
| SCHEMBL9436377 | 0.80 | TSHR (0.35) | — | |
| SCHEMBL6014342 | 0.79 | — | — | |
| SCHEMBL7873521 | 0.73 | — | — | |
| SCHEMBL1060663 | 0.70 | TSHR (0.30) | — | |
| SCHEMBL9549154 | 0.67 | — | — | |
| SCHEMBL6036511 | 0.67 | — | — | |
| SCHEMBL30898370 | 0.66 | TSHR (0.35) | — | |
| SCHEMBL701684 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9540515-B2 | Fluorescence quenching azo dyes, their methods of preparation and use | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2017-01-10 | — | — | US | disclosed |
| US-20130116415-A1 | FLUORESCENCE QUENCHING AZO DYES, THEIR METHODS OF PREPARATION AND USE | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2013-05-09 | — | — | US | disclosed |
| US-8377641-B2 | Fluorescence quenching azo dyes, their methods of preparation and use | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2013-02-19 | — | — | US | disclosed |
| US-20120064633-A1 | FLUORESCENCE QUENCHING AZO DYES, THEIR METHODS OF PREPARATION AND USE | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2012-03-15 | — | — | US | disclosed |
| US-8084588-B2 | Fluorescence quenching azo dyes, their methods of preparation and use | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-20090053821-A1 | FLUORESCENCE QUENCHING AZO DYES, THEIR METHODS OF PREPARATION AND USE | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2009-02-26 | — | — | US | disclosed |
| US-7439341-B2 | Fluorescence quenching azo dyes, their methods of preparation and use | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2008-10-21 | — | — | US | disclosed |
| WO-2005049849-A2 | FLUORESCENCE QUENCHING AZO DYES, THEIR METHODS OF PREPARATION AND USE | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2005-06-02 | — | — | WO | disclosed |
| US-20050112673-A1 | Fluorescence quenching azo dyes, their methods of preparation and use | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2005-05-26 | — | — | US | disclosed |
| EP-1001996-A1 | COMPLEX CHEMICAL COMPOUND, SYNTHESIS AND VARIOUS APPLICATIONS OF SAID COMPOUND | BIO MERIEUX (FR) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999007749-A1 | COMPLEX CHEMICAL COMPOUND, SYNTHESIS AND VARIOUS APPLICATIONS OF SAID COMPOUND | BIO MERIEUX (FR) | 1999-02-18 | — | — | WO | disclosed |
| US-5766550-A | NON-SWELLABLE, INSOLUBLE, STABLE MATRIX ONTO WHICH IS ADSORBED A REAGENT TO BE COUPLED TO AN IMMOBILIZED OLIGONUCLEOTIDE PRECURSOR | CITY OF HOPE (US) | 1998-06-16 | — | — | US | disclosed |
| WO-1996028248-A1 | DISPOSABLE REAGENT STORAGE AND DELIVERY CARTRIDGE | CITY OF HOPE (US) | 1996-09-19 | — | — | WO | disclosed |