Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.79 |
| ▸ | HTR2C | P28335 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 3/20 | 0.76 |
| ▸ | PPARG | P37231 | 2/20 | 0.76 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.76 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.76 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.76 |
| ▸ | ALB | P02768 | 1/20 | 0.76 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.74 |
| ▸ | PGR | P06401 | 3/20 | 0.72 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.67 |
| ▸ | APEX1 | P27695 | 3/20 | 0.67 |
| ▸ | ABCC4 | O15439 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cefetamet SCHEMBL6567051 | 1.00 | NR1I2 (0.79) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefetamet SCHEMBL27492189 | 1.00 | NR1I2 (0.79) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefetamet SCHEMBL10587826 | 1.00 | NR1I2 (0.79) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefetamet SCHEMBL8795245 | 1.00 | NR1I2 (0.79) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefetamet SCHEMBL11328620 | 1.00 | NR1I2 (0.79) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefetamet SCHEMBL10587831 | 1.00 | NR1I2 (0.79) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefetamet SCHEMBL151099 | 1.00 | NR1I2 (0.79) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefetamet SCHEMBL65620 | 1.00 | NR1I2 (0.79) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefetamet SCHEMBL9367206 | 1.00 | NR1I2 (0.79) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefetamet SCHEMBL2586142 | 0.99 | NR1I2 (0.78) | NR1I2HTR2CMAPTPPARGSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025698-B1 | CONTROLLED RELEASE FORMULATIONS | ELI LILLY AND COMPANY (US) | 1984-06-13 | — | — | EP | claimed |
| EP-0025698-A2 | Controlled release formulations | ELI LILLY AND COMPANY (US) | 1981-03-25 | — | — | EP | claimed |
| EP-0690864-B1 | CRYSTALLINE CEFTIOFUR FREE ACID | UPJOHN CO (US) | 2001-06-13 | — | — | EP | disclosed |
| US-5869649-A | Process for producing cephalosporin antibiotics | RANBAXY LABORATORIES LTD. (IN) | 1999-02-09 | — | — | US | disclosed |
| EP-0690864-A1 | CRYSTALLINE CEFTIOFUR FREE ACID | PHARMACIA & UPJOHN COMPANY (US) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994020505-A1 | CRYSTALLINE CEFTIOFUR FREE ACID | THE UPJOHN COMPANY (US) | 1994-09-15 | — | — | WO | disclosed |
| US-4716158-A | CEPHALOSPORINS SUITABLE FOR ORAL ADMINISTRATION | SANKYO COMPANY LIMITED (JP) | 1987-12-29 | — | — | US | disclosed |
| US-4680390-A | CEPHALOSPORINS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-07-14 | — | — | US | disclosed |
| EP-0049118-B1 | CEPHALOSPORIN DERIVATIVES, THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |
| US-4486425-A | ANTIBIOTICS | SANKYO COMPANY LIMITED (JP) | 1984-12-04 | — | — | US | disclosed |
| EP-0025698-B1 | CONTROLLED RELEASE FORMULATIONS | ELI LILLY AND COMPANY (US) | 1984-06-13 | — | — | EP | disclosed |
| EP-0049118-A2 | Cephalosporin derivatives, their preparation and compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-04-07 | — | — | EP | disclosed |
| EP-0025698-A2 | Controlled release formulations | ELI LILLY AND COMPANY (US) | 1981-03-25 | — | — | EP | disclosed |