Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.79 |
| ▸ | HTR2C | P28335 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 3/20 | 0.76 |
| ▸ | PPARG | P37231 | 2/20 | 0.76 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.76 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.76 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.76 |
| ▸ | ALB | P02768 | 1/20 | 0.76 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.74 |
| ▸ | PGR | P06401 | 3/20 | 0.72 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.67 |
| ▸ | APEX1 | P27695 | 3/20 | 0.67 |
| ▸ | ABCC4 | O15439 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cefetamet SCHEMBL27492189 | 1.00 | NR1I2 (0.79) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefetamet SCHEMBL10587826 | 1.00 | NR1I2 (0.79) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefetamet SCHEMBL8795245 | 1.00 | NR1I2 (0.79) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefetamet SCHEMBL7863727 | 1.00 | NR1I2 (0.79) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefetamet SCHEMBL11328620 | 1.00 | NR1I2 (0.79) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefetamet SCHEMBL10587831 | 1.00 | NR1I2 (0.79) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefetamet SCHEMBL151099 | 1.00 | NR1I2 (0.79) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefetamet SCHEMBL65620 | 1.00 | NR1I2 (0.79) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefetamet SCHEMBL9367206 | 1.00 | NR1I2 (0.79) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefetamet SCHEMBL2586142 | 0.99 | NR1I2 (0.78) | NR1I2HTR2CMAPTPPARGSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612729-B1 | Pyridine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-04-23 | — | — | EP | claimed |
| EP-0187209-B1 | PROCESS FOR THE PREPARATION OF CEPHALOSPORINS | F. HOFFMANN-LA ROCHE AG (CH) | 1992-01-08 | — | — | EP | claimed |
| US-20040087787-A1 | Novel thioester derivatives of thiazolyl acetic acid and their use in the preparation of cephalosporin compounds | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2004-05-06 | — | — | US | disclosed |
| EP-1399429-A1 | 1,3,4-OXADIAZOL-2-YL THIOESTERS AND THEIR USE FOR ACYLATING 7-AMINOCEPHALOSPORINS | Orchid Chemicals and Pharmaceuticals Ltd (IN) | 2004-03-24 | — | — | EP | disclosed |
| EP-1347970-A1 | NOVEL THIOESTER DERIVATIVES OF THIAZOLYL ACETIC ACID AND THEIR USE IN THE PREPARATION OF CEPHALOSPORIN COMPOUNDS | Orchid Chemicals and Pharmaceuticals Limited (IN) | 2003-10-01 | — | — | EP | disclosed |
| WO-2003004477-A1 | 1,3,4-OXADIAZOL-2-YL THIOESTERS AND THEIR USE FOR ACYLATING 7-AMINOCEPHALOSPORINS | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2003-01-16 | — | — | WO | disclosed |
| WO-2002053563-A1 | NOVEL THIOESTER DERIVATIVES OF THIAZOLYL ACETIC ACID AND THEIR USE IN THE PREPARATION OF CEPHALOSPORIN COMPOUNDS | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2002-07-11 | — | — | WO | disclosed |
| US-6388070-B1 | CHEMICAL INTERMEDIATE | ORCHID CHEMICALS & PHARMACEUTICALS LTD. (IN) | 2002-05-14 | — | — | US | disclosed |
| US-6384215-B1 | REACTING 4-HALO-2-METHOXYIMINO-3-OXO-BUTYRIC ACID WITH 2-MERCAPTO-1,3,4-OXADIAZOLE TO PRODUCE 2-MERCAPTO-1,3,4-OXADIAZOLYL-4-HALO-2-METHOXYIMINO BUTYRIC ACID; REACTING WITH 7-AMINO-CEPHEM CARBOXYLIC ACID AND THIOUREA | ORCHID CHEMICALS & PHARMACEUTICALS LTD. (IN) | 2002-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087787-A1 | Novel thioester derivatives of thiazolyl acetic acid and their use in the preparation of cephalosporin compounds | ACOT7, ACACA, COASY | NR1I2 2701/4885HTR2C 4739/4885MAPT 2940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.