Hydrochloric Acid

Hydrochloric Acid

SCHEMBL7863747

C1CNCCNCCCNCCNC1.[Cl-].[Cl-].[Ru+2]

nearest known ligand 0.82

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Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.32
CHRM1 known ✓ P11229 1/20 0.32
CXCR4 P61073 8/20 0.82
SMN1; SMN2 Q16637 1/20 0.82
HIF1A Q16665 1/20 0.55
MAPT P10636 1/20 0.55
PDE4A P27815 1/20 0.55
KDR P35968 1/20 0.55
ALDH1A1 P00352 1/20 0.54
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35
CYP2C9 P11712 1/20 0.35
MEN1 O00255 1/20 0.32
ADRA2C P18825 1/20 0.32
CCR2 P41597 1/20 0.32
CXCL12 P48061 1/20 0.32
BLM P54132 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8504380 0.91 CXCR4 (0.82) CXCR4SMN1; SMN2HIF1AMAPTPDE4A
Hydrochloric Acid SCHEMBL152762 0.91 CXCR4 (0.82) CXCR4SMN1; SMN2HIF1AMAPTPDE4A
Hydrochloric Acid SCHEMBL30641652 0.91 CXCR4 (0.82) CXCR4SMN1; SMN2HIF1AMAPTPDE4A
Hydrochloric Acid SCHEMBL8501945 0.91 CXCR4 (0.82) CXCR4SMN1; SMN2HIF1AMAPTPDE4A
Hydrochloric Acid SCHEMBL8502474 0.91 CXCR4 (0.82) CXCR4SMN1; SMN2HIF1AMAPTPDE4A
Hydrochloric Acid SCHEMBL7864264 0.91 CXCR4 (0.82) CXCR4SMN1; SMN2HIF1AMAPTPDE4A
SCHEMBL576838 0.91 CXCR4 (1.00) CXCR4SMN1; SMN2HIF1AMAPTPDE4A
SCHEMBL9947670 0.91 CXCR4 (1.00) CXCR4SMN1; SMN2HIF1AMAPTPDE4A
SCHEMBL8503965 0.91 CXCR4 (1.00) CXCR4SMN1; SMN2HIF1AMAPTPDE4A
SCHEMBL577659 0.91 CXCR4 (1.00) CXCR4SMN1; SMN2HIF1AMAPTPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0729938-B1 A method for producing aryl alkyl hydroperoxides MITSUI CHEMICALS INC (JP) 2001-09-05 EP disclosed
US-6028193-A CATALYZING THE OXIDATION REACTION IN PRESENCE OF A TRANSITION METAL COMPLEX WHICH CONTAINS A CYCLIC POLYFUNCTIONAL AMINE COMPOUND HAVING AT LEAST THREE NITROGEN ATOMS IN THE RING FORMING MOLECULAR MITSUI CHEMICALS, INC. (JP) 2000-02-22 US disclosed
US-5945572-A Method for producing aryl alkyl hydroperoxides MITSUI CHEMICALS, INC. (JP) 1999-08-31 US disclosed
US-5847227-A Method for producing aryl alkyl hydroperoxides MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-12-08 US disclosed
EP-0729938-A2 A method for producing aryl alkyl hydroperoxides MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-09-04 EP disclosed