Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.47 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6513165 | 1.00 | PTGS2 (0.47) | PTGS2PTGS1SCDFLT3CYP2C9 | |
| SCHEMBL6516134 | 1.00 | PTGS2 (0.47) | PTGS2PTGS1SCDFLT3CYP2C9 | |
| SCHEMBL13593045 | 0.80 | SCD (0.57) | PTGS2SCDFLT3 | |
| SCHEMBL6511674 | 0.80 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL6516070 | 0.80 | PTGS2 (0.52) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL5314070 | 0.80 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL6511613 | 0.80 | PTGS2 (0.52) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL5312684 | 0.80 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL6514031 | 0.80 | PTGS2 (0.69) | PTGS2PTGS1SCDFLT3 | |
| SCHEMBL6517008 | 0.79 | PTGS2 (0.46) | PTGS2PTGS1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086097-A1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER INC. (US) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999064415-A1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 1999-12-16 | — | — | WO | disclosed |