SCHEMBL7863833

SCHEMBL7863833

CCCCCCCCC(I)CI

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
TSHR P16473 1/20 0.42
THRB P10828 1/20 0.42
DNM1 Q05193 2/20 0.42
MAPT P10636 1/20 0.41
OPRM1 P35372 1/20 0.40
GPR84 Q9NQS5 3/20 0.38
FDPS P14324 3/20 0.38
SPHK1 Q9NYA1 1/20 0.38
FFAR1 O14842 1/20 0.38
LCK P06239 1/20 0.37
PPARD Q03181 1/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3642082 1.00 LMNA (0.42) LMNATSHRTHRBDNM1MAPT
SCHEMBL7871172 1.00 LMNA (0.42) LMNATSHRTHRBDNM1MAPT
SCHEMBL15383391 1.00 LMNA (0.42) LMNATSHRTHRBDNM1MAPT
SCHEMBL7863856 1.00 LMNA (0.42) LMNATSHRTHRBDNM1MAPT
SCHEMBL7872936 0.97
SCHEMBL28999246 0.91 LMNA (0.37) LMNATSHRTHRBDNM1MAPT
SCHEMBL6275223 0.89
SCHEMBL17461811 0.89
SCHEMBL18324135 0.86 TSHR (0.50) LMNATSHRTHRBDNM1MAPT
SCHEMBL1001552 0.86 TSHR (0.50) LMNATSHRTHRBDNM1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0719839-B1 Phthalocyanine compounds and optical recording media comprising them MITSUI CHEMICALS INC (JP) 2001-07-25 EP disclosed
US-5693396-A NEAR INFRARED LIGHT ABSORBERS MITSUI TOATSU CHEMICALS, INC. (JP) 1997-12-02 US disclosed
EP-0719839-A2 Phthalocyanine compounds and optical recording media comprising them MITSUI TOATSU CHEMICALS, Inc. (JP) 1996-07-03 EP disclosed