SCHEMBL7863863

SCHEMBL7863863

C=CC(=C)C.[Zr]C1C=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
HTR6 P50406 1/20 0.31
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL8383611 0.84 HTR2A (0.38) TP53HTR6HTR2A
SCHEMBL16296388 0.82 HTR2A (0.41) ALDH1A1TP53HTR6HTR2A
SCHEMBL29758183 0.82 HTR2A (0.41) ALDH1A1TP53HTR6HTR2A
SCHEMBL814489 0.82 HTR2A (0.41) ALDH1A1TP53HTR6HTR2A
Chloromethane SCHEMBL8149410 0.80 HTR2A (0.38) TP53HTR6HTR2A
Methylamine SCHEMBL27634217 0.80 HTR2A (0.42) ALDH1A1TP53HTR6HTR2A
Hydrochloric Acid SCHEMBL5709238 0.80 HTR2A (0.40) TP53HTR6HTR2A
Hydrochloric Acid SCHEMBL28723796 0.80 HTR2A (0.40) TP53HTR6HTR2A
Bromide SCHEMBL6903238 0.80 HTR2A (0.40) TP53HTR6HTR2A
Hydrochloric Acid SCHEMBL812666 0.80 HTR2A (0.40) TP53HTR6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1119575-A1 BRIDGED METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 2001-08-01 EP disclosed
WO-2000020426-A1 BRIDGED METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 2000-04-13 WO disclosed